IPO13 and EIF3I

Data Source:
HPRD (in vitro)

		IPO13	EIF3I
Description		importin 13	eukaryotic translation initiation factor 3 subunit I
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GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Extracellular Exosome Eukaryotic Translation Initiation Factor 3 Complex, EIF3m
	Molecular Function	Protein Binding	RNA Binding Translation Initiation Factor Activity Protein Binding
	Biological Process	Protein Import Into Nucleus	Formation Of Cytoplasmic Translation Initiation Complex Cytoplasmic Translational Initiation Translational Initiation
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		17 interacting genes: ALX1 CRX EIF1AX GK HMBOX1 MAGOH NPSR1 NUP50 PAX3 PAX6 PBX4 PITX1 PSMA1 RAN RBM8A RPL5 UBE2I	12 interacting genes: EIF3A EIF3B EIF4G1 ERCC6 ESR1 EXOSC6 LIG4 METTL3 PAXIP1 SUMO4 TGFB1 TGFBR2
Entrez ID		9670	8668
HPRD ID		13742	04884
Ensembl ID		ENSG00000117408	ENSG00000084623
Uniprot IDs		O94829	Q13347 Q5U0F4
PDB IDs		2X19 2XWU 3ZJY	6YBT 6ZMW 6ZON 6ZP4 6ZVJ 7A09
Enriched GO Terms of Interacting Partners?
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