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EIF3I and SUMO4
Data Source:
HPRD
(in vivo)
EIF3I
SUMO4
Description
eukaryotic translation initiation factor 3 subunit I
small ubiquitin like modifier 4
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Eukaryotic Translation Initiation Factor 3 Complex
Eukaryotic 43S Preinitiation Complex
Eukaryotic 48S Preinitiation Complex
Extracellular Exosome
Eukaryotic Translation Initiation Factor 3 Complex, EIF3m
Nucleus
SUMO Ligase Complex
Molecular Function
RNA Binding
Translation Initiation Factor Activity
Protein Binding
Molecular_function
Protein Tag
Ubiquitin-like Protein Ligase Binding
Biological Process
Formation Of Cytoplasmic Translation Initiation Complex
Cytoplasmic Translational Initiation
Translational Initiation
Protein Sumoylation
Cellular Response To Oxidative Stress
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of DNA Binding
Negative Regulation Of DNA Binding
Negative Regulation Of Transcription, DNA-templated
Regulation Of Protein Localization To Nucleus
Pathways
L13a-mediated translational silencing of Ceruloplasmin expression
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS
Dupuytren's disease (
28886342
)
Interacting Genes
12 interacting genes:
EIF3A
EIF3B
EIF4G1
ERCC6
ESR1
EXOSC6
LIG4
METTL3
PAXIP1
SUMO4
TGFB1
TGFBR2
75 interacting genes:
ACADM
ACO2
ACTG1
ALDOA
ARHGDIA
ATP5F1B
CALR
CAT
CCT2
CCT5
CCT6A
CCT7
CLIC1
DNAJA1
DNAJB11
EIF3I
ENO1
ENO2
FOS
G6PD
GAPDH
GMPS
GSTP1
HNRNPD
HNRNPF
HNRNPH1
HNRNPL
HSPA1B
HSPA5
HSPA8
HSPA9
HSPD1
IDH1
IDH3A
IMPDH2
JUN
LDHB
LMNA
LMNB1
MRPS22
NFKBIA
NR3C1
PA2G4
PAFAH1B3
PDIA3
PDIA6
PGK1
PHB
PHGDH
PITHD1
PPA1
PRDX2
PRDX3
PRDX4
PRDX6
PRPS1
PSMC2
RACK1
RPSA
SF3B4
SPINT2
STAT1
STAT3
STIP1
STOML2
STRAP
TFAP2A
TOP2A
TPM3
TUBA1C
TXNL1
UBE2V1
VCP
VDAC1
ZPR1
Entrez ID
8668
387082
HPRD ID
04884
10584
Ensembl ID
ENSG00000084623
ENSG00000177688
Uniprot IDs
Q13347
Q5U0F4
Q6EEV6
PDB IDs
6YBT
6ZMW
6ZON
6ZP4
6ZVJ
7A09
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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