CD63 and CD9

Data Source:
HPRD (in vivo)

		CD63	CD9
Description		CD63 molecule	CD9 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleoplasm Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Endosome Membrane Platelet Dense Granule Membrane Intrinsic Component Of Plasma Membrane Late Endosome Membrane Endosome Lumen Multivesicular Body Membrane Azurophil Granule Membrane Melanosome Intracellular Membrane-bounded Organelle Extracellular Exosome Multivesicular Body, Internal Vesicle	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Membrane Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Platelet Alpha Granule Membrane Protein-containing Complex Extracellular Exosome Extracellular Vesicle
	Molecular Function	Protein Binding	Integrin Binding Protein Binding
	Biological Process	Positive Regulation Of Receptor Internalization Platelet Degranulation Cell-matrix Adhesion Protein Transport Cell Migration Cellular Protein Localization Endosome To Melanosome Transport Neutrophil Degranulation Pigment Granule Maturation Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Integrin-mediated Signaling Pathway	Platelet Degranulation Cell Adhesion Fusion Of Sperm To Egg Plasma Membrane Involved In Single Fertilization Glial Cell Migration Myoblast Fusion Involved In Skeletal Muscle Regeneration Platelet Activation Paranodal Junction Assembly Receptor Internalization Sperm-egg Recognition Negative Regulation Of Cellular Component Movement Cellular Response To Low-density Lipoprotein Particle Stimulus Negative Regulation Of Platelet Aggregation
Pathways		Platelet degranulation Neutrophil degranulation	Platelet degranulation Acrosome Reaction and Sperm:Oocyte Membrane Binding Uptake and function of diphtheria toxin
Drugs			C31G
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Cardiac Troponin-T levels ( 31014085) Refractive error ( 32231278)	Colorectal cancer ( 24836286) Colorectal cancer or advanced adenoma ( 30510241) Mean platelet volume ( 22139419 32888494 27863252) Paclitaxel-induced neuropathy ( 23776197) Platelet count ( 26805783 22139419)
Interacting Genes		18 interacting genes: AP4M1 CD82 CD9 F2RL1 GLP1R HLA-DMB HLA-DRA ITGA6 PI4K2A PTGFRN SDC1 SDCBP SLC22A1 SLC22A2 SRF TIMP1 TMEM80 VKORC1	25 interacting genes: ADAM2 ADRB2 CD19 CD36 CD38 CD53 CD59 CD63 CD81 CLN8 HBEGF IGSF8 ITGA2 ITGA3 ITGA5 ITGB1 KIT ODF4 PRKCA PTGFRN SERPINH1 SLC22A1 SLC22A2 TSPAN4 VKORC1
Entrez ID		967	928
HPRD ID		01121	00880
Ensembl ID		ENSG00000135404	ENSG00000010278
Uniprot IDs		A0A024RB05 P08962	A6NNI4 B4DK09 P21926
PDB IDs			6K4J 6RLR 6Z1V 6Z20
Enriched GO Terms of Interacting Partners?
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