CD9 and SERPINH1

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		CD9	SERPINH1
Description		CD9 molecule	serpin family H member 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Membrane Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Platelet Alpha Granule Membrane Protein-containing Complex Extracellular Exosome Extracellular Vesicle	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Raft Collagen-containing Extracellular Matrix
	Molecular Function	Integrin Binding Protein Binding	RNA Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Collagen Binding Unfolded Protein Binding
	Biological Process	Platelet Degranulation Cell Adhesion Fusion Of Sperm To Egg Plasma Membrane Involved In Single Fertilization Glial Cell Migration Myoblast Fusion Involved In Skeletal Muscle Regeneration Platelet Activation Paranodal Junction Assembly Receptor Internalization Sperm-egg Recognition Negative Regulation Of Cellular Component Movement Cellular Response To Low-density Lipoprotein Particle Stimulus Negative Regulation Of Platelet Aggregation	Chondrocyte Development Involved In Endochondral Bone Morphogenesis Response To Unfolded Protein Negative Regulation Of Endopeptidase Activity Collagen Fibril Organization Collagen Biosynthetic Process Protein Maturation
Pathways		Platelet degranulation Acrosome Reaction and Sperm:Oocyte Membrane Binding Uptake and function of diphtheria toxin	Collagen biosynthesis and modifying enzymes
Drugs		C31G
Diseases
GWAS		Colorectal cancer ( 24836286) Colorectal cancer or advanced adenoma ( 30510241) Mean platelet volume ( 22139419 32888494 27863252) Paclitaxel-induced neuropathy ( 23776197) Platelet count ( 26805783 22139419)	Coronary artery disease ( 29212778 33020668) Height ( 28552196 20881960 22021425 25282103 25429064 31562340 28270201) Hip circumference adjusted for BMI ( 25673412) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 28448500)
Interacting Genes		25 interacting genes: ADAM2 ADRB2 CD19 CD36 CD38 CD53 CD59 CD63 CD81 CLN8 HBEGF IGSF8 ITGA2 ITGA3 ITGA5 ITGB1 KIT ODF4 PRKCA PTGFRN SERPINH1 SLC22A1 SLC22A2 TSPAN4 VKORC1	18 interacting genes: BAG6 BRCA2 C1QL3 CD9 CDK9 CEP70 COL26A1 ESR2 FEZ1 H1-5 KLF13 LINC01554 NSG2 PPARG SLC2A4 SLC35F6 UBQLN4 UBTF
Entrez ID		928	871
HPRD ID		00880	02968
Ensembl ID		ENSG00000010278	ENSG00000149257
Uniprot IDs		A6NNI4 B4DK09 P21926	A0A024R5K8 A8K259 P50454
PDB IDs		6K4J 6RLR 6Z1V 6Z20
Enriched GO Terms of Interacting Partners?
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