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CD63 and TIMP1
Data Source:
BioGRID
(affinity chromatography technology, affinity chromatography technology)
HPRD
(two hybrid, in vivo)
CD63
TIMP1
Description
CD63 molecule
TIMP metallopeptidase inhibitor 1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Nucleoplasm
Lysosomal Membrane
Plasma Membrane
Integral Component Of Plasma Membrane
Cell Surface
Endosome Membrane
Platelet Dense Granule Membrane
Intrinsic Component Of Plasma Membrane
Late Endosome Membrane
Endosome Lumen
Multivesicular Body Membrane
Azurophil Granule Membrane
Melanosome
Intracellular Membrane-bounded Organelle
Extracellular Exosome
Multivesicular Body, Internal Vesicle
Extracellular Region
Basement Membrane
Extracellular Space
Endoplasmic Reticulum Lumen
Extracellular Matrix
Platelet Alpha Granule Lumen
Extracellular Exosome
Molecular Function
Protein Binding
Protease Binding
Cytokine Activity
Protein Binding
Growth Factor Activity
Metalloendopeptidase Inhibitor Activity
Zinc Ion Binding
Peptidase Inhibitor Activity
Biological Process
Positive Regulation Of Receptor Internalization
Platelet Degranulation
Cell-matrix Adhesion
Protein Transport
Cell Migration
Cellular Protein Localization
Endosome To Melanosome Transport
Neutrophil Degranulation
Pigment Granule Maturation
Regulation Of Vascular Endothelial Growth Factor Signaling Pathway
Regulation Of Potassium Ion Transmembrane Transport
Positive Regulation Of Integrin-mediated Signaling Pathway
Cell Activation
Connective Tissue Replacement Involved In Inflammatory Response Wound Healing
Platelet Degranulation
Aging
Positive Regulation Of Cell Population Proliferation
Response To Hormone
Response To Organic Substance
Negative Regulation Of Endopeptidase Activity
Cytokine-mediated Signaling Pathway
Extracellular Matrix Disassembly
Response To Cytokine
Negative Regulation Of Apoptotic Process
Negative Regulation Of Catalytic Activity
Response To Peptide Hormone
Post-translational Protein Modification
Cellular Protein Metabolic Process
Negative Regulation Of Membrane Protein Ectodomain Proteolysis
Cartilage Development
Cellular Response To UV-A
Negative Regulation Of Trophoblast Cell Migration
Negative Regulation Of Metallopeptidase Activity
Regulation Of Integrin-mediated Signaling Pathway
Pathways
Platelet degranulation
Neutrophil degranulation
Platelet degranulation
Activation of Matrix Metalloproteinases
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Interleukin-10 signaling
Interleukin-4 and Interleukin-13 signaling
Post-translational protein phosphorylation
Drugs
Diseases
GWAS
Advanced age-related macular degeneration (
26691988
)
Cardiac Troponin-T levels (
31014085
)
Refractive error (
32231278
)
Interacting Genes
18 interacting genes:
AP4M1
CD82
CD9
F2RL1
GLP1R
HLA-DMB
HLA-DRA
ITGA6
PI4K2A
PTGFRN
SDC1
SDCBP
SLC22A1
SLC22A2
SRF
TIMP1
TMEM80
VKORC1
8 interacting genes:
CD63
ECH1
EEF1B2
MMP1
MMP2
MMP3
MYOC
RECQL5
Entrez ID
967
7076
HPRD ID
01121
02371
Ensembl ID
ENSG00000135404
ENSG00000102265
Uniprot IDs
A0A024RB05
P08962
B4DJK3
P01033
Q6FGX5
PDB IDs
1D2B
1LQN
1OO9
1UEA
2J0T
3MA2
3V96
6MAV
6N9D
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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