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CD63 and F2RL1
Data Source:
BioGRID
(two hybrid)
CD63
F2RL1
Description
CD63 molecule
F2R like trypsin receptor 1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Nucleoplasm
Lysosomal Membrane
Plasma Membrane
Integral Component Of Plasma Membrane
Cell Surface
Endosome Membrane
Platelet Dense Granule Membrane
Intrinsic Component Of Plasma Membrane
Late Endosome Membrane
Endosome Lumen
Multivesicular Body Membrane
Azurophil Granule Membrane
Melanosome
Intracellular Membrane-bounded Organelle
Extracellular Exosome
Multivesicular Body, Internal Vesicle
Early Endosome
Golgi Apparatus
Plasma Membrane
Integral Component Of Plasma Membrane
Pseudopodium
Molecular Function
Protein Binding
G-protein Alpha-subunit Binding
G Protein-coupled Receptor Activity
Signaling Receptor Binding
Protein Binding
Thrombin-activated Receptor Activity
G-protein Beta-subunit Binding
Signaling Receptor Activity
Biological Process
Positive Regulation Of Receptor Internalization
Platelet Degranulation
Cell-matrix Adhesion
Protein Transport
Cell Migration
Cellular Protein Localization
Endosome To Melanosome Transport
Neutrophil Degranulation
Pigment Granule Maturation
Regulation Of Vascular Endothelial Growth Factor Signaling Pathway
Regulation Of Potassium Ion Transmembrane Transport
Positive Regulation Of Integrin-mediated Signaling Pathway
T Cell Activation Involved In Immune Response
Positive Regulation Of Leukocyte Chemotaxis
Positive Regulation Of Cytokine Production Involved In Immune Response
Positive Regulation Of Glomerular Filtration
Inflammatory Response
G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Blood Coagulation
Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Regulation Of Blood Coagulation
Positive Regulation Of Cell Migration
Positive Regulation Of Actin Filament Depolymerization
Positive Regulation Of Pseudopodium Assembly
Chemokine Production
Interferon-gamma Production
Interleukin-1 Beta Production
Interleukin-10 Production
Negative Regulation Of Chemokine Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of Superoxide Anion Generation
Positive Regulation Of Toll-like Receptor 2 Signaling Pathway
Negative Regulation Of Toll-like Receptor 3 Signaling Pathway
Positive Regulation Of Toll-like Receptor 3 Signaling Pathway
Positive Regulation Of Toll-like Receptor 4 Signaling Pathway
Positive Regulation Of Rho Protein Signal Transduction
Neutrophil Activation
Vasodilation
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Eosinophil Degranulation
Positive Regulation Of GTPase Activity
Innate Immune Response
Cell-cell Junction Maintenance
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of JNK Cascade
Negative Regulation Of JNK Cascade
Positive Regulation Of JNK Cascade
Leukocyte Migration
Positive Regulation Of Chemotaxis
Positive Regulation Of Positive Chemotaxis
Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway
Defense Response To Virus
Positive Regulation Of Phagocytosis, Engulfment
Establishment Of Endothelial Barrier
Positive Regulation Of ERK1 And ERK2 Cascade
Thrombin-activated Receptor Signaling Pathway
Leukocyte Proliferation
Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium
Mature Conventional Dendritic Cell Differentiation
Positive Regulation Of Renin Secretion Into Blood Stream
Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production
Pathways
Platelet degranulation
Neutrophil degranulation
Peptide ligand-binding receptors
G alpha (q) signalling events
Drugs
Diseases
GWAS
Advanced age-related macular degeneration (
26691988
)
Cardiac Troponin-T levels (
31014085
)
Refractive error (
32231278
)
Serum bilirubin levels x sex interaction in metabolic syndrome (
30621171
)
Interacting Genes
18 interacting genes:
AP4M1
CD82
CD9
F2RL1
GLP1R
HLA-DMB
HLA-DRA
ITGA6
PI4K2A
PTGFRN
SDC1
SDCBP
SLC22A1
SLC22A2
SRF
TIMP1
TMEM80
VKORC1
76 interacting genes:
ABCC8
ABHD14A
ADCY2
ARL6IP1
ATP2A2
ATP2B1
ATP2C1
BSG
CANX
CAPN1
CAPN2
CAPNS1
CBL
CD63
CD81
CLPTM1
CNN3
COPS5
CRLS1
CTNNA1
CTSG
DNMT3L
ELANE
ERGIC3
F2
GJB6
GJC2
GPRASP1
HERPUD1
HLA-E
HMOX2
HSPA1B
ICAM2
KDELR1
KLC1
LMNA
MFSD10
MORN4
NAT14
NBPF15
OSTC
P4HTM
PHLDA1
PIGU
PLG
PPM1J
PRNP
PRRT2
PRTN3
PSMC3
PTDSS2
QSER1
R3HDM1
RGR
RTN1
RTN4
SCN1B
SDHD
SLC12A5
SLC18B1
SLC1A4
SLC31A2
SLC32A1
SLC35A1
SLC39A13
SLC43A2
ST14
SYNGR2
TMBIM1
TMED1
TMEM161A
TMEM62
TMX2
WFS1
YIPF1
YIPF6
Entrez ID
967
2150
HPRD ID
01121
02960
Ensembl ID
ENSG00000135404
ENSG00000164251
Uniprot IDs
A0A024RB05
P08962
P55085
PDB IDs
5NDD
5NDZ
5NJ6
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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