TLK2 and ASF1B

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		TLK2	ASF1B
Description		tousled like kinase 2	anti-silencing function 1B histone chaperone
Image
GO Annotations	Cellular Component	Nucleus Intermediate Filament Perinuclear Region Of Cytoplasm	Chromatin Nucleoplasm Protein-containing Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Identical Protein Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Protein Binding Histone Binding
	Biological Process	Regulation Of Chromatin Assembly Or Disassembly Chromatin Organization Protein Phosphorylation Cellular Response To DNA Damage Stimulus Cell Cycle Chromosome Segregation Negative Regulation Of Autophagy Peptidyl-serine Phosphorylation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Intracellular Signal Transduction Cellular Response To Gamma Radiation	Blastocyst Hatching DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Spermatogenesis Cell Differentiation
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Heel bone mineral density ( 30598549) Lifespan ( 25918517)
Interacting Genes		17 interacting genes: ASF1A ASF1B AURKA CEP70 DMAP1 FEZ1 FEZ2 FRMD6 GMCL1 IRF4 IRF7 MBP PAX5 PAX6 TLK1 UBE2I YWHAZ	13 interacting genes: ASF1A CDIN1 CHAF1A CHAF1B H3-3A H3C3 H3C6 H4-16 H4C6 HCFC1 TAF1 TLK1 TLK2
Entrez ID		11011	55723
HPRD ID		10527	16460
Ensembl ID		ENSG00000146872	ENSG00000105011
Uniprot IDs		B4DUC2 J3QLK5 Q86UE8	A0A024R7G4 Q9NVP2
PDB IDs		5O0Y	5BNX 5BO0
Enriched GO Terms of Interacting Partners?
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