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APOBEC3B and MIR145
Data Source:
BioGRID
(unspecified method)
APOBEC3B
MIR145
Description
apolipoprotein B mRNA editing enzyme catalytic subunit 3B
microRNA 145
Image
No pdb structure
GO Annotations
Cellular Component
P-body
Nucleus
Nucleoplasm
Cytoplasm
Extracellular Exosome
Molecular Function
RNA Binding
Cytidine Deaminase Activity
Protein Binding
Zinc Ion Binding
Deoxycytidine Deaminase Activity
RNA Polymerase II Complex Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
Cytidine Deamination
Negative Regulation Of Transposition
Cytidine To Uridine Editing
Innate Immune Response
Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate
Defense Response To Virus
DNA Cytosine Deamination
DNA Demethylation
Regulation Of Smooth Muscle Contraction
Negative Regulation Of Cardiac Muscle Hypertrophy
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Ectodermal Cell Differentiation
Positive Regulation Of Fibroblast Migration
Negative Regulation Of Angiogenesis
Actin Cytoskeleton Organization
Negative Regulation Of Cell Migration
Negative Regulation Of Interleukin-16 Production
Positive Regulation Of Interleukin-10 Production
Regulation Of Collagen Biosynthetic Process
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Vascular Associated Smooth Muscle Cell Differentiation
Myofibroblast Differentiation
Angiotensin-activated Signaling Pathway
Positive Regulation Of Macrophage Activation
Establishment Or Maintenance Of Cell Type Involved In Phenotypic Switching
Positive Regulation Of Macrophage Differentiation
Mesodermal Cell Differentiation
Negative Regulation Of Smooth Muscle Cell Proliferation
Negative Regulation Of Inflammatory Response
Negative Regulation Of Protein Kinase B Signaling
Aorta Smooth Muscle Tissue Morphogenesis
Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Phenotypic Switching
Negative Regulation Of Somatic Stem Cell Population Maintenance
Negative Regulation Of Somatic Stem Cell Division
Negative Regulation Of Vascular Associated Smooth Muscle Cell Dedifferentiation
Positive Regulation Of Cardiac Vascular Smooth Muscle Cell Differentiation
Pathways
mRNA Editing: C to U Conversion
Formation of the Editosome
Drugs
Diseases
GWAS
Asthma exacerbations in inhaled corticosteroid treatment (
30697902
)
Breast cancer (
29059683
)
Response to methotrexate in juvenile idiopathic arthritis (
24709693
)
Interacting Genes
61 interacting genes:
AGR2
BNIP2
MIR1-1
MIR1-2
MIR106A
MIR10B
MIR128-1
MIR128-2
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A2
MIR19A
MIR19B1
MIR200A
MIR200B
MIR205
MIR20A
MIR20B
MIR21
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR9-1
MIR9-2
MIR9-3
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
MSL2
79 interacting genes:
ADARB1
APOBEC3B
AQR
C1QBP
DARS1
DDX1
DDX21
DDX3X
DHX36
EIF2AK2
EPRS1
ERAL1
FAM98A
FUS
G3BP2
HARS2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP6
LARP7
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
NONO
NUDT16L1
NUDT21
PDCD11
PGAM5
PRMT1
PTBP1
PTBP3
PUF60
PUM1
RARS1
RBM14
RBM4
RTCA
RTCB
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SYNCRIP
TAF15
TENT2
TIAL1
TRA2A
TRA2B
U2SURP
UPF1
UTP20
YBX1
YBX3
ZFR
ZNF346
Entrez ID
9582
406937
HPRD ID
06169
Ensembl ID
ENSG00000179750
ENSG00000276365
Uniprot IDs
Q9UH17
PDB IDs
2NBQ
5CQD
5CQH
5CQI
5CQK
5SXG
5SXH
5TD5
5TKM
6NFK
6NFL
6NFM
Enriched GO Terms of Interacting Partners
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