ATP5MF and CAPNS1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATP5MF	CAPNS1
Description		ATP synthase membrane subunit f	calpain small subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Integral Component Of Membrane Nuclear Membrane Proton-transporting ATP Synthase Complex, Coupling Factor F(o)	Cytosol Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Proton-transporting ATP Synthase Activity, Rotational Mechanism	Calcium-dependent Cysteine-type Endopeptidase Activity Calcium Ion Binding Protein Binding
	Biological Process	ATP Biosynthetic Process Cristae Formation Mitochondrial ATP Synthesis Coupled Proton Transport Proton Transmembrane Transport	Proteolysis Positive Regulation Of Cell Population Proliferation Regulation Of Macroautophagy Extracellular Matrix Disassembly Cornification
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation	Degradation of the extracellular matrix Degradation of the extracellular matrix Formation of the cornified envelope Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Drugs			PD150606
Diseases
GWAS
Interacting Genes		14 interacting genes: ARL8B CAPNS1 CCDC137 CDC42 CRELD1 FBP1 HAP1 KDM1A LPP NDUFA6 NECTIN2 PRPF4 RPLP1 ZFPL1	20 interacting genes: AGTRAP ARHGEF6 ARR3 ATP5MF CAPN1 CAPN2 CAST CDC42 CDK4 DRG1 F2RL1 GET4 GNB2 IL2RG LRRCC1 PPARGC1A RAB1A STAT3 TERF1 TRAF5
Entrez ID		9551	826
HPRD ID		16520	00240
Ensembl ID		ENSG00000241468	ENSG00000126247
Uniprot IDs		P56134	A0A0C4DGQ5 P04632
PDB IDs			1KFU 1KFX 4PHJ 4PHK 4PHM 4WQ2 4WQ3 5D69 6QLB
Enriched GO Terms of Interacting Partners?
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