CAPNS1 and ATP5MF

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CAPNS1	ATP5MF
Description		calpain small subunit 1	ATP synthase membrane subunit f
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Membrane Extracellular Exosome	Nucleus Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Integral Component Of Membrane Nuclear Membrane Proton-transporting ATP Synthase Complex, Coupling Factor F(o)
	Molecular Function	Calcium-dependent Cysteine-type Endopeptidase Activity Calcium Ion Binding Protein Binding	Proton-transporting ATP Synthase Activity, Rotational Mechanism
	Biological Process	Proteolysis Positive Regulation Of Cell Population Proliferation Regulation Of Macroautophagy Extracellular Matrix Disassembly Cornification	ATP Biosynthetic Process Cristae Formation Mitochondrial ATP Synthesis Coupled Proton Transport Proton Transmembrane Transport
Pathways		Degradation of the extracellular matrix Degradation of the extracellular matrix Formation of the cornified envelope Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models	Formation of ATP by chemiosmotic coupling Cristae formation
Drugs		PD150606
Diseases
GWAS
Interacting Genes		20 interacting genes: AGTRAP ARHGEF6 ARR3 ATP5MF CAPN1 CAPN2 CAST CDC42 CDK4 DRG1 F2RL1 GET4 GNB2 IL2RG LRRCC1 PPARGC1A RAB1A STAT3 TERF1 TRAF5	14 interacting genes: ARL8B CAPNS1 CCDC137 CDC42 CRELD1 FBP1 HAP1 KDM1A LPP NDUFA6 NECTIN2 PRPF4 RPLP1 ZFPL1
Entrez ID		826	9551
HPRD ID		00240	16520
Ensembl ID		ENSG00000126247	ENSG00000241468
Uniprot IDs		A0A0C4DGQ5 P04632	P56134
PDB IDs		1KFU 1KFX 4PHJ 4PHK 4PHM 4WQ2 4WQ3 5D69 6QLB
Enriched GO Terms of Interacting Partners?
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