CAPNS1 and ARR3

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CAPNS1	ARR3
Description		calpain small subunit 1	arrestin 3
Image
GO Annotations	Cellular Component	Cytosol Plasma Membrane Membrane Extracellular Exosome	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm Synapse
	Molecular Function	Calcium-dependent Cysteine-type Endopeptidase Activity Calcium Ion Binding Protein Binding	G Protein-coupled Receptor Binding Opsin Binding Protein Binding Phosphoprotein Binding
	Biological Process	Proteolysis Positive Regulation Of Cell Population Proliferation Regulation Of Macroautophagy Extracellular Matrix Disassembly Cornification	Regulation Of Protein Phosphorylation G Protein-coupled Receptor Internalization Signal Transduction Visual Perception
Pathways		Degradation of the extracellular matrix Degradation of the extracellular matrix Formation of the cornified envelope Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Drugs		PD150606
Diseases
GWAS
Interacting Genes		20 interacting genes: AGTRAP ARHGEF6 ARR3 ATP5MF CAPN1 CAPN2 CAST CDC42 CDK4 DRG1 F2RL1 GET4 GNB2 IL2RG LRRCC1 PPARGC1A RAB1A STAT3 TERF1 TRAF5	20 interacting genes: ADRB2 AP3B1 CAPNS1 CLTC CSNK2A1 DVL2 FSHR GNMT MAP2K7 MARCHF8 OPN1MW OPN4 PLK4 PTAFR RCOR2 RHO RNASE6 SRC ZBTB43 ZNF496
Entrez ID		826	407
HPRD ID		00240	02358
Ensembl ID		ENSG00000126247	ENSG00000120500
Uniprot IDs		A0A0C4DGQ5 P04632	P36575
PDB IDs		1KFU 1KFX 4PHJ 4PHK 4PHM 4WQ2 4WQ3 5D69 6QLB	1XEH 2A34
Enriched GO Terms of Interacting Partners?
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