CAPNS1 and DRG1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CAPNS1	DRG1
Description		calpain small subunit 1	developmentally regulated GTP binding protein 1
Image
GO Annotations	Cellular Component	Cytosol Plasma Membrane Membrane Extracellular Exosome	Nucleus Cytoplasm Cytosol Polysome Membrane Nuclear Body
	Molecular Function	Calcium-dependent Cysteine-type Endopeptidase Activity Calcium Ion Binding Protein Binding	GTPase Activity Protein Binding GTP Binding Microtubule Binding Transcription Factor Binding Potassium Ion Binding Identical Protein Binding
	Biological Process	Proteolysis Positive Regulation Of Cell Population Proliferation Regulation Of Macroautophagy Extracellular Matrix Disassembly Cornification	Cytoplasmic Translation Transcription, DNA-templated Multicellular Organism Development Positive Regulation Of Microtubule Polymerization Regulation Of Mitotic Spindle Assembly
Pathways		Degradation of the extracellular matrix Degradation of the extracellular matrix Formation of the cornified envelope Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Drugs		PD150606
Diseases
GWAS			Fish- and plant-related diet ( 32066663) Neutrophil count ( 32888494 27863252) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Sum basophil neutrophil counts ( 27863252) Thyroid stimulating hormone levels ( 32769997)
Interacting Genes		20 interacting genes: AGTRAP ARHGEF6 ARR3 ATP5MF CAPN1 CAPN2 CAST CDC42 CDK4 DRG1 F2RL1 GET4 GNB2 IL2RG LRRCC1 PPARGC1A RAB1A STAT3 TERF1 TRAF5	16 interacting genes: CAPNS1 CLDN1 COIL LNX1 LYL1 MEOX2 PHC2 PTEN RWDD1 SKIL SRPK2 SSX2IP STK16 TAL1 UBE2I ZC3H15
Entrez ID		826	4733
HPRD ID		00240	16034
Ensembl ID		ENSG00000126247	ENSG00000185721
Uniprot IDs		A0A0C4DGQ5 P04632	Q9Y295
PDB IDs		1KFU 1KFX 4PHJ 4PHK 4PHM 4WQ2 4WQ3 5D69 6QLB	2EKI
Enriched GO Terms of Interacting Partners?
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