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HOXA1 and RBCK1
Data Source:
BioGRID
(protein complementation assay)
HOXA1
RBCK1
Description
homeobox A1
RANBP2-type and C3HC4-type zinc finger containing 1
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Ubiquitin Ligase Complex
Cytosol
LUBAC Complex
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Identical Protein Binding
Sequence-specific DNA Binding
Sequence-specific Double-stranded DNA Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Identical Protein Binding
Ubiquitin Binding
Metal Ion Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Multicellular Organism Development
Sensory Perception Of Sound
Optokinetic Behavior
Anatomical Structure Morphogenesis
Abducens Nerve Formation
Outer Ear Morphogenesis
Positive Regulation Of Transcription By RNA Polymerase II
Embryonic Neurocranium Morphogenesis
Inner Ear Development
Artery Morphogenesis
Regulation Of Behavior
Cognition
Neuromuscular Process
Artery Development
Semicircular Canal Formation
Cochlea Development
Cochlea Morphogenesis
Protein Polyubiquitination
I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Viral Process
Negative Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
T Cell Receptor Signaling Pathway
Positive Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Necroptotic Process
Protein Linear Polyubiquitination
Positive Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Regulation of TNFR1 signaling
TNFR1-induced NFkappaB signaling pathway
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
Bosley-Salih-Alorainy syndrome and Athabascan brainstem dysgenesis syndrome
GWAS
Chronic venous disease (
28374850
)
Macular thickness (
30535121
)
Multiple sclerosis (
31604244
)
Small cell lung carcinoma (
28604730
)
Tonsillectomy (
27182965
28928442
)
Night sleep phenotypes (
27126917
)
Interacting Genes
292 interacting genes:
ADAM12
ADAMTSL4
AGXT
ALG13
ALPP
AMMECR1
AMOT
ANKS1A
ARID5A
ARMC7
ATG9B
ATP23
BAG4
BAHD1
BATF2
BHLHB9
BLCAP
BLZF1
BSCL2
BUD31
C11orf1
C11orf16
CATSPER1
CCDC120
CCDC33
CCN3
CCN4
CCN5
CCNK
CD164
CDPF1
CERCAM
CFP
CHIC2
CHRD
CHRDL2
CNFN
CNNM3
COL8A1
CREB5
CUTA
CXCL16
CYHR1
CYP21A2
CYSRT1
DOCK2
DOCK3
DOK3
DTX2
DUSP10
DUSP22
EFEMP1
EFEMP2
EGFL7
ENKD1
EPDR1
ESM1
ESR2
EVA1B
FAAP100
FAM219B
FAM221A
FBLN1
FHL3
FHL5
FOXH1
FOXN1
FRS3
FST
FUCA2
GAS8
GATA1
GCM2
GDF15
GNE
GP9
GPS2
GRN
GSTP1
GUCD1
HEXB
HEXIM2
HEY2
HOXB9
HR
HSD3B7
ID3
IGFL1
IGFN1
INCA1
INO80B
IRX6
ITGB4
KCTD9
KDM1A
KPRP
KRT31
KRT33B
KRT34
KRT35
KRT37
KRT38
KRT40
KRT81
KRT82
KRT83
KRTAP1-1
KRTAP1-3
KRTAP1-5
KRTAP10-1
KRTAP10-10
KRTAP10-11
KRTAP10-3
KRTAP10-4
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP11-1
KRTAP12-1
KRTAP12-2
KRTAP12-3
KRTAP12-4
KRTAP13-2
KRTAP13-3
KRTAP13-4
KRTAP15-1
KRTAP19-6
KRTAP19-7
KRTAP2-3
KRTAP2-4
KRTAP23-1
KRTAP26-1
KRTAP3-2
KRTAP3-3
KRTAP4-1
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP4-5
KRTAP4-7
KRTAP5-11
KRTAP5-2
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-9
KRTAP6-1
KRTAP6-2
KRTAP6-3
KRTAP9-2
KRTAP9-3
KRTAP9-4
KRTAP9-8
LASP1
LCE1A
LCE1B
LCE1C
LCE1D
LCE1F
LCE2A
LCE2B
LCE2C
LCE2D
LCE3C
LCE3E
LCE4A
LCE5A
LGALS13
LGALS4
LMX1B
LNX1
LONRF1
LPXN
MACO1
MAPKBP1
MDFI
MFAP2
MGAT5B
MKRN3
MYO15B
MYPOP
N4BP2L2
NBPF19
NCK2
NECTIN2
NEDD9
NEK6
NELL2
NFKBID
NOTCH2NLA
NR1D2
NTN4
NXF1
ODF1
OIT3
P2RY6
PAX6
PBX2
PCSK5
PCYOX1
PHETA1
PIK3R1
PIN1
PITX1
PITX2
PKNOX1
PLEKHN1
PLLP
PLSCR1
PLSCR2
PLSCR3
PLSCR4
PPP1R32
PRICKLE4
PRMT6
PROP1
PSMB1
PTH1R
PVR
QARS1
RALGDS
RANBP3
RBCK1
RBP3
RBPMS
RCHY1
RGS17
RGS19
RGS20
RNF208
RSPO2
RTN4R
SCT
SDCBP
SIVA1
SLC15A3
SLC23A1
SLIT1
SLPI
SNRPB
SNRPC
SPATA12
SPATA18
SPRY1
SPRY2
SPRY3
SPRY4
SSC4D
SSUH2
STX11
SUV39H1
TBC1D10C
TBX15
TCF19
TCF3
TEKT4
TEKT5
TGFB1
TGM7
THAP7
TLE5
TNS2
TRAF1
TRAF2
TRAF4
TRAPPC6A
TRIM42
TRIM55
TRIM63
TRIM8
TRIP6
TSPAN4
UBL5
UNKL
VASN
VWC2
VWC2L
WDR83
WWOX
YIPF3
YPEL3
ZBTB16
ZIM2
ZMAT1
ZNF417
ZNF587
ZNF688
ZNF774
ZNF837
ZNF843
65 interacting genes:
APP
ARNT2
BACH1
CREB5
CREBBP
ENKD1
GLYCTK
HGS
HOXA1
HOXC8
IL16
IREB2
KANK2
LNX1
MALT1
MAP3K1
MAPKBP1
MKRN2
NAA10
NDUFAF3
NEDD4
NR1I2
OTUB2
OTUD6A
PAN2
PCGF2
PRKCA
PRKN
PSMA1
PSMD4
RNF181
RNF31
SMURF1
SOCS6
SYCE1
TNFAIP3
TP53
TRAF1
TRIM21
TRIM25
TRIM65
TRIML1
TSSK3
TTC23
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2G1
UBE2K
UBE2L3
UBE2L6
UBE2N
UBE2S
UBE2U
UCHL5
UHRF2
USP15
USP2
USP21
USP32
USP49
USP7
ZNF414
Entrez ID
3198
10616
HPRD ID
00843
16643
Ensembl ID
ENSG00000105991
ENSG00000125826
Uniprot IDs
P49639
A6PVJ6
A6PVK0
Q9BYM8
PDB IDs
2CRC
2LGY
4DBG
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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