HOXA1 and TRIM42

Data Source:
BioGRID (two hybrid, two hybrid)

		HOXA1	TRIM42
Description		homeobox A1	tripartite motif containing 42
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Zinc Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Sensory Perception Of Sound Optokinetic Behavior Anatomical Structure Morphogenesis Abducens Nerve Formation Outer Ear Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Embryonic Neurocranium Morphogenesis Inner Ear Development Artery Morphogenesis Regulation Of Behavior Cognition Neuromuscular Process Artery Development Semicircular Canal Formation Cochlea Development Cochlea Morphogenesis
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases		Bosley-Salih-Alorainy syndrome and Athabascan brainstem dysgenesis syndrome
GWAS		Chronic venous disease ( 28374850) Macular thickness ( 30535121) Multiple sclerosis ( 31604244) Small cell lung carcinoma ( 28604730) Tonsillectomy ( 27182965 28928442)	Bipolar disorder (body mass index interaction) ( 24322204) Refractive astigmatism ( 25367360)
Interacting Genes		292 interacting genes: ADAM12 ADAMTSL4 AGXT ALG13 ALPP AMMECR1 AMOT ANKS1A ARID5A ARMC7 ATG9B ATP23 BAG4 BAHD1 BATF2 BHLHB9 BLCAP BLZF1 BSCL2 BUD31 C11orf1 C11orf16 CATSPER1 CCDC120 CCDC33 CCN3 CCN4 CCN5 CCNK CD164 CDPF1 CERCAM CFP CHIC2 CHRD CHRDL2 CNFN CNNM3 COL8A1 CREB5 CUTA CXCL16 CYHR1 CYP21A2 CYSRT1 DOCK2 DOCK3 DOK3 DTX2 DUSP10 DUSP22 EFEMP1 EFEMP2 EGFL7 ENKD1 EPDR1 ESM1 ESR2 EVA1B FAAP100 FAM219B FAM221A FBLN1 FHL3 FHL5 FOXH1 FOXN1 FRS3 FST FUCA2 GAS8 GATA1 GCM2 GDF15 GNE GP9 GPS2 GRN GSTP1 GUCD1 HEXB HEXIM2 HEY2 HOXB9 HR HSD3B7 ID3 IGFL1 IGFN1 INCA1 INO80B IRX6 ITGB4 KCTD9 KDM1A KPRP KRT31 KRT33B KRT34 KRT35 KRT37 KRT38 KRT40 KRT81 KRT82 KRT83 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-3 KRTAP10-4 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP13-2 KRTAP13-3 KRTAP13-4 KRTAP15-1 KRTAP19-6 KRTAP19-7 KRTAP2-3 KRTAP2-4 KRTAP23-1 KRTAP26-1 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP4-7 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LASP1 LCE1A LCE1B LCE1C LCE1D LCE1F LCE2A LCE2B LCE2C LCE2D LCE3C LCE3E LCE4A LCE5A LGALS13 LGALS4 LMX1B LNX1 LONRF1 LPXN MACO1 MAPKBP1 MDFI MFAP2 MGAT5B MKRN3 MYO15B MYPOP N4BP2L2 NBPF19 NCK2 NECTIN2 NEDD9 NEK6 NELL2 NFKBID NOTCH2NLA NR1D2 NTN4 NXF1 ODF1 OIT3 P2RY6 PAX6 PBX2 PCSK5 PCYOX1 PHETA1 PIK3R1 PIN1 PITX1 PITX2 PKNOX1 PLEKHN1 PLLP PLSCR1 PLSCR2 PLSCR3 PLSCR4 PPP1R32 PRICKLE4 PRMT6 PROP1 PSMB1 PTH1R PVR QARS1 RALGDS RANBP3 RBCK1 RBP3 RBPMS RCHY1 RGS17 RGS19 RGS20 RNF208 RSPO2 RTN4R SCT SDCBP SIVA1 SLC15A3 SLC23A1 SLIT1 SLPI SNRPB SNRPC SPATA12 SPATA18 SPRY1 SPRY2 SPRY3 SPRY4 SSC4D SSUH2 STX11 SUV39H1 TBC1D10C TBX15 TCF19 TCF3 TEKT4 TEKT5 TGFB1 TGM7 THAP7 TLE5 TNS2 TRAF1 TRAF2 TRAF4 TRAPPC6A TRIM42 TRIM55 TRIM63 TRIM8 TRIP6 TSPAN4 UBL5 UNKL VASN VWC2 VWC2L WDR83 WWOX YIPF3 YPEL3 ZBTB16 ZIM2 ZMAT1 ZNF417 ZNF587 ZNF688 ZNF774 ZNF837 ZNF843	145 interacting genes: ADAMTSL4 AQP1 ARMC7 ARNT2 ARRDC3 ATG9A AXIN1 BACH2 BEX2 C1orf109 CARD9 CATSPER1 CBY2 CCDC120 CCDC24 CCDC33 CDCA7L CEP70 CERK CHCHD2 CHRD CREB5 CYSRT1 EFEMP2 EFHC2 EMD FAM124B FAM90A1 FBLN1 FCHO1 FNDC3B GLI1 GLRX3 GLYCTK GNE GOLGA2 GUCD1 HOXA1 HOXC8 HSD3B7 IGFN1 IHO1 IKZF3 IL16 IQUB KCTD9 KLHL38 KPRP KRT13 KRT15 KRT34 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP3-2 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-7 KRTAP9-3 L3MBTL2 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3C LCE3D LCE3E LCE4A LCE5A LNX1 LONRF1 LZTS2 MAGOHB MAPKBP1 MEIS2 MEOX2 MFAP1 MGAT5B MID2 MTUS2 MVP NBPF19 NEK8 NOTCH2NLA OTX1 PCSK5 PHLDA1 PLSCR1 PLSCR4 PNMA1 POU4F2 PRKAB2 PROP1 PSMA1 PSMD9 PTGER3 R3HDM2 RAMAC RCOR3 RUNX1T1 SCNM1 SHFL SLIT1 SMARCC1 SMCP SPAG8 SSX2IP STK16 TASOR2 TCAF1 TFAP2D TLX3 TMEM150A TRAF1 TRAF2 TRAPPC2B TRIM23 TRIM27 TXNDC5 VGLL3 VPS37A VWC2L YIPF3 YWHAQ YY1 ZBTB1 ZNF330 ZNF414
Entrez ID		3198	287015
HPRD ID		00843	15559
Ensembl ID		ENSG00000105991	ENSG00000155890
Uniprot IDs		P49639	Q8IWZ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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