CIAO1 and TOP3B

		CIAO1	TOP3B
Description		cytosolic iron-sulfur assembly component 1	DNA topoisomerase III beta
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GO Annotations	Cellular Component	Cytoplasm MMXD Complex CIA Complex	Condensed Chromosome Nucleus
	Molecular Function	Protein Binding	DNA Binding RNA Binding DNA Topoisomerase Activity DNA Topoisomerase Type I (single Strand Cut, ATP-independent) Activity Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Chromosome Segregation Positive Regulation Of Cell Population Proliferation Iron-sulfur Cluster Assembly Protein Maturation By Iron-sulfur Cluster Transfer	DNA Topological Change Chromosome Segregation
Pathways		Cytosolic iron-sulfur cluster assembly
Drugs
Diseases
GWAS			Attention function in attention deficit hyperactive disorder ( 26174813) Bipolar disorder ( 31043756) Diastolic blood pressure ( 29208002) Response to selective serotonin reuptake inhibitors in depression ( 27622933)
Interacting Genes		18 interacting genes: APP CCDC7 CIAO2A CIAO2B GOLM1 HAUS3 MEOX1 MEOX2 PGRMC1 RGS2 SF1 SHISA6 SLC4A7 SRPK1 TCP10L TOP3B URI1 WT1	24 interacting genes: ADAMTSL4 AXIN2 BHLHB9 C1QBP CENPF CHD8 CHIC2 CIAO1 FASTK FBLN5 GRN KANK2 KRTAP4-12 MID2 PNMA2 RECQL5 SNRPB SPRED2 SSX2IP TRIM41 UPF2 ZFPM1 ZNF250 ZNF408
Entrez ID		9391	8940
HPRD ID		16057	04662
Ensembl ID		ENSG00000144021	ENSG00000100038
Uniprot IDs		O76071	A0A024R1C2 A8K4N2 O95985
PDB IDs		3FM0	5GVC 5GVE
Enriched GO Terms of Interacting Partners?
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