TIFA and LNX2

Data Source:
BioGRID (two hybrid)

		TIFA	LNX2
Description		TRAF interacting protein with forkhead associated domain	ligand of numb-protein X 2
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GO Annotations	Cellular Component	Cytoplasm
	Molecular Function	Protein Binding	Protein Binding PDZ Domain Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Cytoplasmic Pattern Recognition Receptor Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Protein Homooligomerization
Pathways		Alpha-protein kinase 1 signaling pathway
Drugs
Diseases
GWAS		Body mass index ( 26426971) Rheumatoid arthritis ( 30891314)	Body mass index ( 26426971 28892062) Large B-cell lymphoma ( 21471979) Mean platelet volume ( 32888494 27863252) Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494 27863252) Response to cytadine analogues (cytosine arabinoside) ( 24483146)
Interacting Genes		23 interacting genes: AP1M1 ARHGEF39 DVL2 GSDME IRAK1 KANK2 LNX1 LNX2 NIF3L1 NTAQ1 NUDT18 NXF1 PRKAA2 RIPPLY3 RPL9 SDCBP SDCBP2 TIFAB TNFAIP8 TRAF1 TRAF2 TRAF6 TXN2	89 interacting genes: ATP5F1B C10orf88 CABP4 CBX4 CCT3 CDK2 CDK4 CDKN2C CRK CXADR DDA1 DRAP1 EAF2 FANCG FHL3 GADD45A GJD2 GLRX3 GRAP2 GRB2 IGSF5 IL16 INMT IP6K2 L3MBTL2 LGALS14 LNX1 LRRC8E MAP2K5 MAPK9 MCM7 MDGA1 MLX MRFAP1L1 MSRB3 MYLIP NAGK NMD3 NOTCH1 NTAQ1 NUDT14 NUMB OPTN PARVG PDZRN3 PDZRN4 PEG10 PHYKPL PIK3R1 PIK3R3 PKDREJ POLR1C PPIH PPIL1 PSMD5 PSMF1 PTCD3 RAB6B RBM17 RLIM RNF138 ROPN1 RPA2 SCLY SCNM1 SFN SH3GLB2 SHISA2 SHTN1 SMARCB1 SRSF11 TAB1 TBC1D7 TCL1A TIFA TRAF1 TRAF2 TUBB UBE2D2 UBE2H UBE2I UBE2T UBE2Z USP2 VTN YJU2 ZNF148 ZNF410 ZNF581
Entrez ID		92610	222484
HPRD ID		09835	10042
Ensembl ID		ENSG00000145365	ENSG00000139517
Uniprot IDs		Q96CG3	Q8N448
PDB IDs		4YM4 4ZGI 5ZUJ 6A33	2VWR 5DIN 5E11 5E1Y 5E21 5E22
Enriched GO Terms of Interacting Partners?
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