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VAPA and CD79A
Data Source:
BioGRID
(two hybrid)
VAPA
CD79A
Description
VAMP associated protein A
CD79a molecule
Image
GO Annotations
Cellular Component
Golgi Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Plasma Membrane
Bicellular Tight Junction
Integral Component Of Membrane
Nuclear Membrane
Vesicle
Azurophil Granule Membrane
Perinuclear Region Of Cytoplasm
Endoplasmic Reticulum Exit Site
Multivesicular Body
Plasma Membrane
External Side Of Plasma Membrane
Integral Component Of Membrane
B Cell Receptor Complex
Membrane Raft
Molecular Function
Protein Binding
Microtubule Binding
Protein Domain Specific Binding
FFAT Motif Binding
Cadherin Binding
Protein Heterodimerization Activity
Transmembrane Signaling Receptor Activity
Protein Binding
Identical Protein Binding
Biological Process
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Endoplasmic Reticulum Organization
Cell Death
Viral Process
Sphingolipid Biosynthetic Process
Neuron Projection Development
Protein Folding In Endoplasmic Reticulum
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Neutrophil Degranulation
Positive Regulation By Host Of Viral Release From Host Cell
Negative Regulation By Host Of Viral Genome Replication
Positive Regulation By Host Of Viral Genome Replication
Membrane Fusion
Protein Localization To Endoplasmic Reticulum
COPII-coated Vesicle Budding
Adaptive Immune Response
B Cell Differentiation
B Cell Proliferation
B Cell Activation
B Cell Receptor Signaling Pathway
Pathways
Sphingolipid de novo biosynthesis
Neutrophil degranulation
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
CD22 mediated BCR regulation
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases
Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
GWAS
Diverticular disease (
30177863
)
FEV1 (
30804560
)
Heel bone mineral density (
30598549
)
Lung function (FEV1/FVC) (
30804560
)
Metabolite levels (
23823483
)
Peak expiratory flow (
30804560
)
Pulmonary function (smoking interaction) (
23284291
)
Brain morphology (MOSTest) (
32665545
)
Interacting Genes
39 interacting genes:
ADGRG7
ADRB2
APOD
APP
AQP6
CACNG1
CD79A
CYB561
CYBRD1
EBAG9
EBP
EGFR
ERBB2
GKN1
HSD17B11
HSD17B13
JAGN1
KCNB1
LEPROTL1
NSF
OPRM1
OSBP
PGRMC2
RETREG3
RMDN2
SCN3B
SEC11C
SIK1
SLC16A7
SLC35B1
TMEM229B
TMEM35A
TMEM86B
TMIE
TMX2
USP20
VAMP1
VAMP2
ZBTB22
181 interacting genes:
ADIPOQ
AGTRAP
ALG10
ALG10B
ALG3
APOD
AQP1
AQP3
ATP6V0C
BCL2L2
BET1
BLK
BLNK
BRICD5
BTN2A2
C14orf180
C1GALT1
C2CD2L
C4orf3
CCDC167
CD19
CD5
CD79B
CDIPT
CLDN1
CLN6
CMTM5
CMTM7
CNIH1
CNIH3
COL4A5
CTSA
CTXN3
CYB561
CYB561A3
CYB561D2
CYB5B
DEFB127
DOLK
EDDM3B
EMC6
EMP1
EMP3
FA2H
FAM241B
FANCA
FATE1
FAXDC2
FCAR
FDFT1
FFAR3
FKBP8
FUNDC2
FXYD3
FYN
GALNT15
GIMAP1
GJB1
GPR42
HACD4
HCLS1
HMOX1
HMOX2
IER3
IGHM
INSIG2
ITGAM
JAGN1
JCHAIN
LAMB1
LCK
LEPROTL1
LHFPL5
LPAR3
LTC4S
LYN
MALL
MARCHF2
MFF
MFSD12
MFSD5
MFSD6
MGLL
MMD2
MOSPD3
MS4A13
MYADM
MYADML2
NAT8
NEU1
NINJ2
NIPAL3
NKG7
ORMDL2
OTOP2
PGAP2
PIGR
PKMYT1
PLP2
PLPP6
PLPPR2
PNLIPRP1
PRAF2
PTCH1
PTPN6
REEP6
RHO
RTP2
SACM1L
SEC22B
SERP1
SFTPC
SLC13A4
SLC13A5
SLC16A12
SLC16A13
SLC30A2
SLC35B1
SLC35B4
SLC38A1
SLC39A2
SLC39A9
SLC41A1
SLC41A2
SLC46A3
SLC66A2
SLC6A12
SLC7A1
SMCO4
SMIM3
STRIT1
STX12
STX3
STX8
SYK
SYNJ2BP
TECR
THBD
TM4SF19
TM4SF4
TMBIM6
TMEM107
TMEM11
TMEM128
TMEM140
TMEM147
TMEM14B
TMEM176A
TMEM187
TMEM19
TMEM218
TMEM222
TMEM229B
TMEM239
TMEM243
TMEM254
TMEM262
TMEM42
TMEM86A
TMEM86B
TMPPE
TNFRSF10C
TRAM1L1
TRARG1
TSNARE1
TSPAN2
TSPO2
UBE2J1
UBIAD1
UNC93B1
VAMP3
VAPA
VAPB
VTI1B
WFDC2
WFS1
YIF1A
YIPF4
YIPF6
ZDHHC15
ZDHHC22
Entrez ID
9218
973
HPRD ID
09299
00203
Ensembl ID
ENSG00000101558
ENSG00000105369
Uniprot IDs
Q9P0L0
P11912
PDB IDs
2RR3
1CV9
Enriched GO Terms of Interacting Partners
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