VAPA and SLC16A7

Data Source:
BioGRID (two hybrid)

		VAPA	SLC16A7
Description		VAMP associated protein A	solute carrier family 16 member 7
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Nuclear Membrane Vesicle Azurophil Granule Membrane Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site	Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Microtubule Binding Protein Domain Specific Binding FFAT Motif Binding Cadherin Binding Protein Heterodimerization Activity	Pyruvate Secondary Active Transmembrane Transporter Activity Protein Binding Monocarboxylic Acid Transmembrane Transporter Activity Lactate Transmembrane Transporter Activity Symporter Activity Pyruvate Transmembrane Transporter Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Cell Death Viral Process Sphingolipid Biosynthetic Process Neuron Projection Development Protein Folding In Endoplasmic Reticulum Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Neutrophil Degranulation Positive Regulation By Host Of Viral Release From Host Cell Negative Regulation By Host Of Viral Genome Replication Positive Regulation By Host Of Viral Genome Replication Membrane Fusion Protein Localization To Endoplasmic Reticulum COPII-coated Vesicle Budding	Monocarboxylic Acid Transport Lactate Transmembrane Transport Transport Across Blood-brain Barrier Pyruvate Transmembrane Transport
Pathways		Sphingolipid de novo biosynthesis Neutrophil degranulation Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Proton-coupled monocarboxylate transport
Drugs			Pyruvic acid
Diseases
GWAS		Diverticular disease ( 30177863) FEV1 ( 30804560) Heel bone mineral density ( 30598549) Lung function (FEV1/FVC) ( 30804560) Metabolite levels ( 23823483) Peak expiratory flow ( 30804560) Pulmonary function (smoking interaction) ( 23284291)	Adventurousness ( 30643258) Calcium levels ( 25972035) General risk tolerance (MTAG) ( 30643258) Hematocrit ( 29403010) Logical memory (delayed recall) in normal cognition ( 29274321) Logical memory (immediate recall) in normal cognition ( 29274321) Response to zileuton treatment in asthma (FEV1 change interaction) ( 26031901) Takayasu arteritis ( 25604533)
Interacting Genes		39 interacting genes: ADGRG7 ADRB2 APOD APP AQP6 CACNG1 CD79A CYB561 CYBRD1 EBAG9 EBP EGFR ERBB2 GKN1 HSD17B11 HSD17B13 JAGN1 KCNB1 LEPROTL1 NSF OPRM1 OSBP PGRMC2 RETREG3 RMDN2 SCN3B SEC11C SIK1 SLC16A7 SLC35B1 TMEM229B TMEM35A TMEM86B TMIE TMX2 USP20 VAMP1 VAMP2 ZBTB22	15 interacting genes: ACSL5 CDIPT COMT CPEB1 FXYD6 GPR25 HMOX1 IFITM3 LEMD1 SFXN1 SMAGP SNTA1 TIMM23 VAPA VTI1B
Entrez ID		9218	9194
HPRD ID		09299	06791
Ensembl ID		ENSG00000101558	ENSG00000118596
Uniprot IDs		Q9P0L0	A0A024RBB2 O60669
PDB IDs		2RR3	7BP3
Enriched GO Terms of Interacting Partners?
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