PDCD5 and LRIF1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PDCD5	LRIF1
Description		programmed cell death 5	ligand dependent nuclear receptor interacting factor 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Exosome	Chromosome, Telomeric Region Barr Body Nucleoplasm Nuclear Matrix Centriolar Satellite
	Molecular Function	DNA Binding Protein Binding Heparin Binding Acetyltransferase Activator Activity Beta-tubulin Binding	Protein Binding Retinoic Acid Receptor Binding
	Biological Process	Apoptotic Process Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Positive Regulation Of Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Protein Insertion Into Mitochondrial Outer Membrane Negative Regulation Of Chaperone-mediated Protein Folding	Regulation Of Transcription, DNA-templated Dosage Compensation By Inactivation Of X Chromosome
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) Immature fraction of reticulocytes ( 32888494) Major depressive disorder ( 23377640) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean platelet volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Platelet count ( 32888494) Red cell distribution width ( 32888494 27863252)	Bone mineral content ( 31790847) Intraocular pressure ( 30591961)
Interacting Genes		15 interacting genes: ACP5 CDC42 CEP126 EEF1G KAT5 KDM1A LRIF1 NUDT3 OTUD5 PICK1 RAD18 TRIM35 UBE2D3 UTP14A VHL	144 interacting genes: AKR1C3 ANKRD24 ANXA1 ANXA7 APLP1 ARL3 ATF3 ATP1B1 BANP BARD1 BMI1 BOC BRD7 BRMS1 CALR CBX1 CBX3 CBX5 CCDC106 CDC42 CDKN1A CDKN2C CETN3 CHD3 CKMT2 COX17 CPE CRACR2A CRADD CRCP CRCT1 DDIT4 EIF6 ESR1 ETHE1 FAS FEZ1 FHL2 FOSL2 FXR1 GADD45G GC GIT1 GPRASP2 GSTM4 H3-4 HAP1 HLA-DQA1 HMGB1 HMOX2 HSPB1 HSPB3 HSPBP1 HSPE1 ID2 IMMT KAT5 KAT7 KBTBD7 KCNE3 KLHL20 KLK10 LAMA4 LAMTOR5 MAD2L1BP MLLT3 MNAT1 MOB4 MPHOSPH6 MRPS12 MRPS6 NACA NOC2L NR3C1 NRBP1 NTAQ1 PAEP PAFAH1B3 PCDHA4 PDCD5 PFDN1 PFN1 PIAS4 PIN1 PLEKHA4 PNP POLR1C POLR2C POLR3F PPARG PQBP1 PRKAB2 PRKAR2A PRMT1 PSG9 PSMD11 PSMD2 PSPC1 RAB27A RAP1B RARA RBM5 RCC1 RFC5 RHOH RIT1 RNF10 RORA RPA2 RPL37A RPLP1 RRM1 S100A8 SAT1 SELENBP1 SERPINB9 SETDB1 SMN1 SNRPN SNU13 SPATA18 SPG7 STX5 SULT1E1 SUPT4H1 SUV39H2 TAF1D TDGF1 TGIF1 THRB TK1 TRBV2 TRDMT1 TSC22D1 TSEN15 TSPAN6 UBE2V2 UNC119 VIM VPS26C WDR62 WWC1 ZNF24 ZNF410
Entrez ID		9141	55791
HPRD ID		06843	17975
Ensembl ID		ENSG00000105185	ENSG00000121931
Uniprot IDs		O14737	Q5T3J3
PDB IDs		1YYB 2CRU 2K6B
Enriched GO Terms of Interacting Partners?
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