PDCD5 and UTP14A

Data Source:
HPRD (two hybrid)

		PDCD5	UTP14A
Description		programmed cell death 5	UTP14A small subunit processome component
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Exosome	Nucleoplasm Nucleolus Cytosol Small-subunit Processome
	Molecular Function	DNA Binding Protein Binding Heparin Binding Acetyltransferase Activator Activity Beta-tubulin Binding	RNA Binding Protein Binding
	Biological Process	Apoptotic Process Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Positive Regulation Of Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Protein Insertion Into Mitochondrial Outer Membrane Negative Regulation Of Chaperone-mediated Protein Folding	RRNA Processing
Pathways			rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) Immature fraction of reticulocytes ( 32888494) Major depressive disorder ( 23377640) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean platelet volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Platelet count ( 32888494) Red cell distribution width ( 32888494 27863252)
Interacting Genes		15 interacting genes: ACP5 CDC42 CEP126 EEF1G KAT5 KDM1A LRIF1 NUDT3 OTUD5 PICK1 RAD18 TRIM35 UBE2D3 UTP14A VHL	46 interacting genes: AKTIP APLP1 APP ARIH2 AXIN1 CCDC106 CCDC85B CEP70 CPE CSNK2A1 CSNK2B DLEU1 GADD45G HNRNPH3 HOOK2 HTT LAMTOR5 LDOC1 LMO1 LSM3 NINL PDCD5 PDZK1IP1 PHF10 PRKCZ PSG1 PTEN PTPRS RABIF RGS1 RHOH RNF10 RPA2 RSRC1 SAT1 SMYD1 SSR1 TERF1 TINAGL1 TP53 TP53BP2 TRDMT1 TXLNB VIM WDR33 ZNF24
Entrez ID		9141	10813
HPRD ID		06843	06712
Ensembl ID		ENSG00000105185	ENSG00000156697
Uniprot IDs		O14737	Q9BVJ6
PDB IDs		1YYB 2CRU 2K6B
Enriched GO Terms of Interacting Partners?
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