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CREB3L1 and PLPP6
Data Source:
BioGRID
(two hybrid)
CREB3L1
PLPP6
Description
cAMP responsive element binding protein 3 like 1
phospholipid phosphatase 6
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Plasma Membrane
Membrane
Integral Component Of Membrane
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Chromatin Binding
Protein Binding
CAMP Response Element Binding
SMAD Binding
Sequence-specific Double-stranded DNA Binding
Protein Binding
Hydrolase Activity
Sphingosine-1-phosphate Phosphatase Activity
Lipid Phosphatase Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Osteoblast Differentiation
Regulation Of Transcription By RNA Polymerase II
Multicellular Organism Development
Negative Regulation Of Gene Expression
Viral Process
Endoplasmic Reticulum Unfolded Protein Response
Positive Regulation Of Collagen Biosynthetic Process
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Negative Regulation Of Transcription, DNA-templated
Extracellular Matrix Constituent Secretion
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Sprouting Angiogenesis
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Cholesterol Biosynthetic Process
Phospholipid Dephosphorylation
Pathways
CREB3 factors activate genes
Cholesterol biosynthesis
Drugs
Diseases
GWAS
Alzheimer's disease or fasting glucose levels (pleiotropy) (
30805717
)
Apolipoprotein A1 levels (
32203549
)
Autism spectrum disorder or schizophrenia (
28540026
)
Fasting blood glucose (
22581228
)
HDL cholesterol levels (
32203549
)
LDL cholesterol (
30275531
)
Medication use (diuretics) (
31015401
)
Offspring birth weight (
31043758
)
Peripheral artery disease (
31285632
)
Schizophrenia (
29483656
)
Systolic blood pressure (
30578418
)
Interacting Genes
194 interacting genes:
ADAM33
ADGRE2
ADIPOQ
AGPAT3
AGPAT4
AGPAT5
ALG8
ANKRD46
AOC3
APOD
AQP10
AQP2
ARV1
ASGR1
BET1
BMP10
BNIP3
BRICD5
C11orf24
C4orf3
C5
CCL4L2
CD53
CD72
CD99L2
CFHR5
CIAO2A
CLN6
CMTM3
CMTM7
CNIH2
COL8A2
COMT
COX20
CREB3
CREB3L3
CREM
CSGALNACT2
CTSA
CTXN3
CXCL16
CYB561D2
CYBC1
CYP4F2
DDIT3
DOLK
EBP
EMP3
ENTPD3
ERG28
ERMP1
FA2H
FAM3C
FAXDC2
FETUB
FXYD3
FXYD6
GAST
GIMAP1
GIMAP5
GOLT1B
GOSR2
GPR151
GPR25
GPR37L1
HACD2
HIF1A
IL1RL1
INSIG2
ITGAM
JAGN1
KCNK1
LEPROTL1
LHFPL5
LPAR3
LTC4S
MAL
MAL2
MALL
MAN2B2
MARCHF2
MFSD5
MGAM
MGST2
MGST3
MMD2
MS4A1
MS4A13
NAPB
NAT8
NEU1
NINJ1
NINJ2
NRM
NSG1
OLFM4
OR10AG1
ORMDL1
ORMDL2
PAQR6
PEDS1-UBE2V1
PEX16
PGAP2
PGRMC1
PLN
PLP1
PLP2
PLPP4
PLPP6
PLPPR2
PMP22
PRKAB2
PTPN9
RFT1
RHBDD1
RHD
RNASE10
RUNX1T1
RUSF1
SACM1L
SCARF1
SCD
SCGB1D1
SEC22A
SEC22B
SEC61G
SEMA4G
SFXN5
SLC13A2
SLC13A3
SLC16A13
SLC2A3
SLC30A8
SLC35A4
SLC35B1
SLC35B2
SLC35B4
SLC35C2
SLC39A2
SLC39A9
SLC52A1
SLC7A1
SMCO4
SMIM1
SPOCK1
SQLE
STX3
STX7
STX8
SYNGR1
SYNJ2BP
TECR
TEX264
TFRC
TIMM23
TIMMDC1
TLCD1
TMBIM6
TMEM11
TMEM120B
TMEM128
TMEM147
TMEM14A
TMEM14B
TMEM14C
TMEM19
TMEM203
TMEM208
TMEM218
TMEM222
TMEM229B
TMEM234
TMEM239
TMEM50B
TMEM86A
TMIE
TNF
TNFRSF10C
TNMD
TRAM1L1
TSPAN2
TSPO
TSPO2
UBIAD1
UNC93B1
VAMP1
VAMP2
VEZT
VKORC1
WFDC2
YIPF6
ZDHHC15
ZDHHC22
ZFPL1
57 interacting genes:
AMIGO1
AQP6
AQP8
BTN2A1
BTNL9
C16orf92
CD79A
CIAO2A
CLDN15
CLDN9
CLEC4M
CLN5
COMT
CREB3L1
EBP
FAM174A
FAM209A
FAM210B
FKBP7
FNDC9
FXYD3
GJB5
GKN1
GORAB
GPX8
HSH2D
IL10RA
IL13RA2
KASH5
LAYN
LDLRAD1
MMGT1
MS4A3
MUC1
NCR3LG1
PDGFRA
PDZK1IP1
PHACTR3
PRLR
PVR
RETREG3
RNF170
RNF5
SEC11C
SHISAL1
SIGLEC12
SLC7A14
SMAGP
SOCS4
SSMEM1
STX1A
SYNE4
SYNPR
TMEM106C
TMIE
TNFRSF10D
VSIR
Entrez ID
90993
403313
HPRD ID
16751
17397
Ensembl ID
ENSG00000157613
ENSG00000205808
Uniprot IDs
B2RA75
Q96BA8
Q8IY26
PDB IDs
Enriched GO Terms of Interacting Partners
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