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PLPP6 and VSIR
Data Source:
BioGRID
(two hybrid)
PLPP6
VSIR
Description
phospholipid phosphatase 6
V-set immunoregulatory receptor
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Membrane
Integral Component Of Membrane
Plasma Membrane
Integral Component Of Membrane
Molecular Function
Protein Binding
Hydrolase Activity
Sphingosine-1-phosphate Phosphatase Activity
Lipid Phosphatase Activity
Protein Binding
Enzyme Binding
Identical Protein Binding
Endopeptidase Activator Activity
Biological Process
Cholesterol Biosynthetic Process
Phospholipid Dephosphorylation
Positive Regulation Of Gene Expression
Positive Regulation Of Endopeptidase Activity
Positive Regulation Of Cell Migration
Zymogen Activation
Negative Regulation Of Interferon-gamma Production
Negative Regulation Of Interleukin-10 Production
Negative Regulation Of Interleukin-17 Production
Negative Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Regulatory T Cell Differentiation
Regulation Of Immune Response
Positive Regulation Of Collagen Catabolic Process
Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation
Negative Regulation Of CD8-positive, Alpha-beta T Cell Proliferation
Pathways
Cholesterol biosynthesis
Drugs
Diseases
GWAS
Interacting Genes
57 interacting genes:
AMIGO1
AQP6
AQP8
BTN2A1
BTNL9
C16orf92
CD79A
CIAO2A
CLDN15
CLDN9
CLEC4M
CLN5
COMT
CREB3L1
EBP
FAM174A
FAM209A
FAM210B
FKBP7
FNDC9
FXYD3
GJB5
GKN1
GORAB
GPX8
HSH2D
IL10RA
IL13RA2
KASH5
LAYN
LDLRAD1
MMGT1
MS4A3
MUC1
NCR3LG1
PDGFRA
PDZK1IP1
PHACTR3
PRLR
PVR
RETREG3
RNF170
RNF5
SEC11C
SHISAL1
SIGLEC12
SLC7A14
SMAGP
SOCS4
SSMEM1
STX1A
SYNE4
SYNPR
TMEM106C
TMIE
TNFRSF10D
VSIR
27 interacting genes:
APOD
ASGR1
ATP6V0C
BMP10
C14orf180
CCL4L2
CLEC7A
CLRN2
CNIH3
DOLK
MS4A13
PLPP6
PLPPR2
PLSCR1
SLC35B1
SLC35B4
SMAD3
SMCO4
TMEM100
TMEM14C
TMEM218
TMEM229B
TMEM97
TNF
TSPAN2
TSPO2
VAMP3
Entrez ID
403313
64115
HPRD ID
17397
15160
Ensembl ID
ENSG00000205808
ENSG00000107738
Uniprot IDs
Q8IY26
Q9H7M9
PDB IDs
6MVL
6OIL
6U6V
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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