PLPP6 and AQP8

		PLPP6	AQP8
Description		phospholipid phosphatase 6	aquaporin 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Mitochondrial Membrane Apical Part Of Cell
	Molecular Function	Protein Binding Hydrolase Activity Sphingosine-1-phosphate Phosphatase Activity Lipid Phosphatase Activity	Protein Binding Water Channel Activity
	Biological Process	Cholesterol Biosynthetic Process Phospholipid Dephosphorylation	Water Transport Transmembrane Transport Cellular Response To CAMP
Pathways		Cholesterol biosynthesis	Detoxification of Reactive Oxygen Species Passive transport by Aquaporins
Drugs
Diseases
GWAS			Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 27400856)
Interacting Genes		57 interacting genes: AMIGO1 AQP6 AQP8 BTN2A1 BTNL9 C16orf92 CD79A CIAO2A CLDN15 CLDN9 CLEC4M CLN5 COMT CREB3L1 EBP FAM174A FAM209A FAM210B FKBP7 FNDC9 FXYD3 GJB5 GKN1 GORAB GPX8 HSH2D IL10RA IL13RA2 KASH5 LAYN LDLRAD1 MMGT1 MS4A3 MUC1 NCR3LG1 PDGFRA PDZK1IP1 PHACTR3 PRLR PVR RETREG3 RNF170 RNF5 SEC11C SHISAL1 SIGLEC12 SLC7A14 SMAGP SOCS4 SSMEM1 STX1A SYNE4 SYNPR TMEM106C TMIE TNFRSF10D VSIR	6 interacting genes: CYBC1 PLP2 PLPP6 SERP1 STX12 TMEM120B
Entrez ID		403313	343
HPRD ID		17397	04778
Ensembl ID		ENSG00000205808	ENSG00000103375
Uniprot IDs		Q8IY26	O94778
PDB IDs
Enriched GO Terms of Interacting Partners?
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