STARD13 and KIF1B

Data Source:
HPRD (in vivo, two hybrid)

		STARD13	KIF1B
Description		StAR related lipid transfer domain containing 13	kinesin family member 1B
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GO Annotations	Cellular Component	Lipid Droplet Cytosol Mitochondrial Membrane	Mitochondrion Kinesin Complex Microtubule Microtubule Associated Complex Synaptic Vesicle Axon Dendrite Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Neuron Projection Axon Cytoplasm
	Molecular Function	GTPase Activator Activity Protein Binding Lipid Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Kinesin Binding Kinase Binding Scaffold Protein Binding
	Biological Process	Signal Transduction Actin Cytoskeleton Organization Regulation Of Rho Protein Signal Transduction Endothelial Cell Migration Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Endothelial Tube Lumen Extension	Apoptotic Process Microtubule-based Movement Neuron-neuron Synaptic Transmission Neuromuscular Synaptic Transmission Anterograde Axonal Transport Positive Regulation Of Gene Expression Vesicle-mediated Transport Cytoskeleton-dependent Intracellular Transport Lysosome Localization Response To Rotenone Anterograde Neuronal Dense Core Vesicle Transport Retrograde Neuronal Dense Core Vesicle Transport Cellular Response To Nerve Growth Factor Stimulus Protein Localization To Cell Periphery
Pathways		Rho GTPase cycle	COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases			Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Body mass index in asthmatics ( 23517042) Colorectal cancer or advanced adenoma ( 30510241) Diverticular disease ( 30177863) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Intracranial aneurysm ( 20364137) Plasma amyloid beta peptide concentrations (ABx-40) ( 24535457) Platelet count ( 32888494) Plateletcrit ( 32888494) Red blood cell count ( 32888494)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Hand grip strength ( 29691431) Hematocrit ( 27863252) Hepatitis B virus-related hepatocellular carcinoma ( 29246937) Hepatocellular carcinoma ( 20676096) Lateral orbital frontal cortex volume ( 31530798) Mean platelet volume ( 22139419 32888494 27863252) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 18997785) Neutrophil count ( 32888494) Platelet count ( 32888494) Virologic severity in Herpes simplex virus type 2 infection ( 29535370) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in non-smokers ( 28443625) White blood cell count ( 32888494)
Interacting Genes		12 interacting genes: ADGRB2 EPB41L1 HMGCR HSP90AA1 HSP90AB1 ITPR1 KIF1B SMAD1 SMARCD3 TAX1BP1 TUBA1A TUBA4A	22 interacting genes: ARHGAP1 BRCA1 CALM1 CHP1 CLIP4 CPEB1 DLG1 DLG2 DLG3 DLG4 DYSF EEF1A1 GIPC1 LAMTOR5 PATJ PGM1 POMP SIAH1 SNTA1 STARD13 TRIM55 YWHAG
Entrez ID		90627	23095
HPRD ID		11607	05818
Ensembl ID		ENSG00000133121	ENSG00000054523
Uniprot IDs		A0A024RDV4 B2R789 B3KRK6 Q9Y3M8	O60333
PDB IDs		2H80 2JW2 2PSO	2EH0
Enriched GO Terms of Interacting Partners?
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