STARD13 and SMARCD3

Data Source:
BioGRID (two hybrid)

		STARD13	SMARCD3
Description		StAR related lipid transfer domain containing 13	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
Image			No pdb structure
GO Annotations	Cellular Component	Lipid Droplet Cytosol Mitochondrial Membrane	Chromatin Nucleus Nucleoplasm SWI/SNF Complex NpBAF Complex NBAF Complex
	Molecular Function	GTPase Activator Activity Protein Binding Lipid Binding	DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Transcription Coactivator Activity Signaling Receptor Binding Transcription Factor Binding Nuclear Hormone Receptor Binding
	Biological Process	Signal Transduction Actin Cytoskeleton Organization Regulation Of Rho Protein Signal Transduction Endothelial Cell Migration Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Endothelial Tube Lumen Extension	Positive Regulation Of Neuroblast Proliferation Secondary Heart Field Specification Cardiac Right Ventricle Formation Neural Retina Development Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Lipid Metabolic Process Muscle Cell Differentiation Regulation Of Protein Binding Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Smooth Muscle Cell Differentiation
Pathways		Rho GTPase cycle	RORA activates gene expression BMAL1:CLOCK,NPAS2 activates circadian gene expression PPARA activates gene expression PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Activation of gene expression by SREBF (SREBP) RMTs methylate histone arginines Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by PPARalpha Circadian Clock RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS		Body mass index in asthmatics ( 23517042) Colorectal cancer or advanced adenoma ( 30510241) Diverticular disease ( 30177863) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Intracranial aneurysm ( 20364137) Plasma amyloid beta peptide concentrations (ABx-40) ( 24535457) Platelet count ( 32888494) Plateletcrit ( 32888494) Red blood cell count ( 32888494)	Eyebrow thickness ( 26926045) Heel bone mineral density ( 30598549) Hematocrit ( 32888494) Hemoglobin ( 32888494) IgG glycosylation ( 23382691) Immunoglobulin light chain (AL) amyloidosis ( 28025584) Multiple myeloma ( 27363682) Red blood cell count ( 32888494)
Interacting Genes		12 interacting genes: ADGRB2 EPB41L1 HMGCR HSP90AA1 HSP90AB1 ITPR1 KIF1B SMAD1 SMARCD3 TAX1BP1 TUBA1A TUBA4A	20 interacting genes: ARHGAP1 CCNE1 ESR1 ESRRA FANCA JUN MAPK14 NR1H4 NR5A1 NR5A2 PBX1 PPARG RARA RARB RARG RORA RXRA SMARCC1 SREBF1 STARD13
Entrez ID		90627	6604
HPRD ID		11607	03440
Ensembl ID		ENSG00000133121	ENSG00000082014
Uniprot IDs		A0A024RDV4 B2R789 B3KRK6 Q9Y3M8	A0A090N8Z9 Q6STE5
PDB IDs		2H80 2JW2 2PSO
Enriched GO Terms of Interacting Partners?
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