KIF1B and CHP1

Data Source:
HPRD (in vitro, two hybrid)

		KIF1B	CHP1
Description		kinesin family member 1B	calcineurin like EF-hand protein 1
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GO Annotations	Cellular Component	Mitochondrion Kinesin Complex Microtubule Microtubule Associated Complex Synaptic Vesicle Axon Dendrite Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Neuron Projection Axon Cytoplasm	Golgi Membrane Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol Plasma Membrane Focal Adhesion Microtubule Cytoskeleton Transport Vesicle Extracellular Exosome
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Kinesin Binding Kinase Binding Scaffold Protein Binding	Protein Kinase Inhibitor Activity Calcium Ion Binding Protein Binding Microtubule Binding Potassium Channel Regulator Activity Kinase Binding Calcium-dependent Protein Binding
	Biological Process	Apoptotic Process Microtubule-based Movement Neuron-neuron Synaptic Transmission Neuromuscular Synaptic Transmission Anterograde Axonal Transport Positive Regulation Of Gene Expression Vesicle-mediated Transport Cytoskeleton-dependent Intracellular Transport Lysosome Localization Response To Rotenone Anterograde Neuronal Dense Core Vesicle Transport Retrograde Neuronal Dense Core Vesicle Transport Cellular Response To Nerve Growth Factor Stimulus Protein Localization To Cell Periphery	Microtubule Bundle Formation Negative Regulation Of Protein Phosphorylation Negative Regulation Of Protein Kinase Activity Protein Export From Nucleus Potassium Ion Transport Vesicle Targeting Vesicle Fusion Small GTPase Mediated Signal Transduction Negative Regulation Of Phosphatase Activity Membrane Docking Hyaluronan Catabolic Process Cytoplasmic Microtubule Organization Negative Regulation Of Protein Ubiquitination Negative Regulation Of Protein Autophosphorylation Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Protein Import Into Nucleus Protein Stabilization Positive Regulation Of Protein Transport Protein Complex Oligomerization Regulation Of Intracellular PH Positive Regulation Of Protein Glycosylation Membrane Organization Membrane Fusion Negative Regulation Of Calcineurin-NFAT Signaling Cascade Positive Regulation Of Phospholipid Biosynthetic Process Cellular Response To Acidic PH Positive Regulation Of Protein Targeting To Membrane Regulation Of Neuron Death
Pathways		COPI-dependent Golgi-to-ER retrograde traffic Kinesins	Hyaluronan uptake and degradation
Drugs			Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Hand grip strength ( 29691431) Hematocrit ( 27863252) Hepatitis B virus-related hepatocellular carcinoma ( 29246937) Hepatocellular carcinoma ( 20676096) Lateral orbital frontal cortex volume ( 31530798) Mean platelet volume ( 22139419 32888494 27863252) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 18997785) Neutrophil count ( 32888494) Platelet count ( 32888494) Virologic severity in Herpes simplex virus type 2 infection ( 29535370) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in non-smokers ( 28443625) White blood cell count ( 32888494)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Essential hypertension (time to event) ( 32589924) Estimated glomerular filtration rate ( 31015462) Ulcerative colitis ( 28067908) White blood cell count ( 32888494)
Interacting Genes		22 interacting genes: ARHGAP1 BRCA1 CALM1 CHP1 CLIP4 CPEB1 DLG1 DLG2 DLG3 DLG4 DYSF EEF1A1 GIPC1 LAMTOR5 PATJ PGM1 POMP SIAH1 SNTA1 STARD13 TRIM55 YWHAG	10 interacting genes: GAPDH KIF1B PRSS23 SLC9A1 SLC9A2 SLC9A3 SLC9A4 SLC9A5 STK17B UBC
Entrez ID		23095	11261
HPRD ID		05818	06101
Ensembl ID		ENSG00000054523	ENSG00000187446
Uniprot IDs		O60333	A0A024R9M9 H0YKE7 Q99653
PDB IDs		2EH0	2E30
Enriched GO Terms of Interacting Partners?
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