KIF1B and CLIP4

Data Source:
BioGRID (two hybrid)

		KIF1B	CLIP4
Description		kinesin family member 1B	CAP-Gly domain containing linker protein family member 4
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GO Annotations	Cellular Component	Mitochondrion Kinesin Complex Microtubule Microtubule Associated Complex Synaptic Vesicle Axon Dendrite Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Neuron Projection Axon Cytoplasm	Nucleus Cytoplasm Microtubule Plus-end Intracellular Membrane-bounded Organelle
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Kinesin Binding Kinase Binding Scaffold Protein Binding	Protein Binding Microtubule Plus-end Binding
	Biological Process	Apoptotic Process Microtubule-based Movement Neuron-neuron Synaptic Transmission Neuromuscular Synaptic Transmission Anterograde Axonal Transport Positive Regulation Of Gene Expression Vesicle-mediated Transport Cytoskeleton-dependent Intracellular Transport Lysosome Localization Response To Rotenone Anterograde Neuronal Dense Core Vesicle Transport Retrograde Neuronal Dense Core Vesicle Transport Cellular Response To Nerve Growth Factor Stimulus Protein Localization To Cell Periphery	Cytoplasmic Microtubule Organization
Pathways		COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Hand grip strength ( 29691431) Hematocrit ( 27863252) Hepatitis B virus-related hepatocellular carcinoma ( 29246937) Hepatocellular carcinoma ( 20676096) Lateral orbital frontal cortex volume ( 31530798) Mean platelet volume ( 22139419 32888494 27863252) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 18997785) Neutrophil count ( 32888494) Platelet count ( 32888494) Virologic severity in Herpes simplex virus type 2 infection ( 29535370) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in non-smokers ( 28443625) White blood cell count ( 32888494)	Metabolite levels ( 23823483)
Interacting Genes		22 interacting genes: ARHGAP1 BRCA1 CALM1 CHP1 CLIP4 CPEB1 DLG1 DLG2 DLG3 DLG4 DYSF EEF1A1 GIPC1 LAMTOR5 PATJ PGM1 POMP SIAH1 SNTA1 STARD13 TRIM55 YWHAG	33 interacting genes: APP CDK5RAP2 CLIP1 CMYA5 DCAF6 DES DST GLP1R HSF2BP JAKMIP2 KIF1B KIFC3 LZTS2 MAGEA12 MAP7 MAP7D1 MEOX2 MYBPC1 MYH3 PDE4DIP PEG10 SIX2 SON TACC3 TAF1 TNNT1 TNNT3 TPM1 TRIM32 TRIP13 TTN TULP3 ZNF114
Entrez ID		23095	79745
HPRD ID		05818	08634
Ensembl ID		ENSG00000054523	ENSG00000115295
Uniprot IDs		O60333	A8K6D0 B7Z936 Q8N3C7
PDB IDs		2EH0	2Z0W
Enriched GO Terms of Interacting Partners?
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