PNMA2 and RPL9

Data Source:
BioGRID (two hybrid, two hybrid)

		PNMA2	RPL9
Description		PNMA family member 2	ribosomal protein L9
Image		No pdb structure
GO Annotations	Cellular Component	Nucleolus	Nucleus Cytosol Ribosome Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit
	Molecular Function	Protein Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding
	Biological Process	Positive Regulation Of Apoptotic Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Cognitive decline rate in late mild cognitive impairment ( 26252872)	Alcohol consumption (drinks per week) ( 30643258)
Interacting Genes		32 interacting genes: BYSL CBX8 CCDC33 CDC37 CNNM3 ENKD1 FAM161A GPATCH2L HAPLN2 INO80B LRR1 MISP MORF4L2 NTAQ1 PPIG PRPF31 PSMA1 RNF6 RNF8 RPL9 RTP5 SCNM1 SDCBP THAP7 TOP3B TTLL10 ZNF408 ZNF417 ZNF587 ZNF669 ZNF688 ZNF785	36 interacting genes: BACH2 BICDL2 CALCOCO2 CBY2 CCDC184 CEP76 CTTN DHPS DRAP1 DUX4 ESR1 FAM9B HMBOX1 HOMEZ KXD1 MOCS2 MTUS2 PNMA2 PPP1R27 PSTPIP1 RALY RPS3 SNRPF SORBS2 SREK1IP1 SRSF3 STAC3 TIFA TNFAIP8L1 TRIM37 UBALD1 USO1 VCP ZBTB14 ZBTB7B ZBTB8A
Entrez ID		10687	6133
HPRD ID		04915	04732
Ensembl ID		ENSG00000240694	ENSG00000163682
Uniprot IDs		Q5U5Z3 Q9UL42	P32969 Q53Z07
PDB IDs			2CQL 4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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