AQP10 and CISD2

Data Source:
BioGRID (two hybrid)

		AQP10	CISD2
Description		aquaporin 10	CDGSH iron sulfur domain 2
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GO Annotations	Cellular Component	Lipid Droplet Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane Intracellular Membrane-bounded Organelle	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Protein-containing Complex Perinuclear Endoplasmic Reticulum
	Molecular Function	Protein Binding Urea Transmembrane Transporter Activity Water Channel Activity Glycerol Channel Activity	RNA Binding Protein Binding Protein Homodimerization Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Water Transport Response To Toxic Substance Glycerol Transport Protein Homotetramerization Cellular Response To Acidic PH Urea Transmembrane Transport	Autophagy Of Mitochondrion Multicellular Organism Aging Regulation Of Autophagy
Pathways		Passive transport by Aquaporins
Drugs
Diseases			Wolfram syndrome (WFS); DIDMOAD syndrome
GWAS		Bipolar disorder ( 31043756) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Non-albumin protein levels ( 29403010) Parkinson's disease progression (motor) ( 33111402) Red cell distribution width ( 32888494) Serum total protein level ( 29403010)	Asthma and attention deficit hyperactivity disorder ( 31619474) Estimated glomerular filtration rate ( 31152163) Primary biliary cholangitis ( 26394269) Schizophrenia ( 28991256) Type 2 diabetes ( 28869590)
Interacting Genes		20 interacting genes: ARL13B CISD2 CREB3L1 CYBC1 ERGIC3 GPR152 GPR37L1 KIR2DL3 LMNA LYVE1 MGST3 NEMP1 PGRMC2 PLP1 PVR SAR1A SCN3B SSMEM1 SYT2 TMEM167B	58 interacting genes: AIG1 APOL2 APP AQP10 BCL2L2 BET1 BMP10 BTN2A2 C14orf180 C2CD2L C4orf3 CDIPT CFHR5 CLDN10 CLN6 CYBC1 EHHADH EMD FAM241B GALNT15 GAST GPR37L1 HHATL IER3 KIR2DL3 LEPROTL1 LRP10 MAN2B2 MIP NAPB NRG4 NSG1 PGAP2 PLPP4 PLPPR2 PNKP POMGNT1 RTP2 RUSF1 SEC22A SERP2 SLC13A3 SLC35B4 SMIM1 SNORC SPP1 STX12 STX7 THSD7B TMEM187 TMEM243 TMEM43 TMEM86A TSPAN33 TTPA VAMP4 VKORC1L1 YIPF6
Entrez ID		89872	493856
HPRD ID		07361	17413
Ensembl ID		ENSG00000143595	ENSG00000145354
Uniprot IDs		Q96PS8	Q8N5K1
PDB IDs		6F7H	3FNV 4OO7 4OOA
Enriched GO Terms of Interacting Partners?
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