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CPNE1 and RDX
Data Source:
HPRD
(two hybrid, in vitro)
CPNE1
RDX
Description
copine 1
radixin
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Nuclear Membrane
Azurophil Granule Membrane
Extracellular Exosome
Extracellular Space
Plasma Membrane
Microvillus
Adherens Junction
Focal Adhesion
Apical Plasma Membrane
Lamellipodium
Filopodium
T-tubule
Midbody
Cortical Actin Cytoskeleton
Cleavage Furrow
Cell Tip
Extracellular Exosome
Cell Periphery
Molecular Function
Phosphatidylserine Binding
Endopeptidase Activity
Transporter Activity
Calcium Ion Binding
Protein Binding
Calcium-dependent Phospholipid Binding
Identical Protein Binding
NF-kappaB Binding
RNA Binding
Actin Binding
Protein Binding
Cadherin Binding
Protein Kinase A Binding
ATPase Binding
Biological Process
Proteolysis
Lipid Metabolic Process
Negative Regulation Of Gene Expression
Vesicle-mediated Transport
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Neutrophil Degranulation
Negative Regulation Of DNA Binding
Positive Regulation Of Neuron Differentiation
Glycerophospholipid Biosynthetic Process
Positive Regulation Of Protein Kinase B Signaling
Cellular Response To Calcium Ion
Negative Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Neuron Projection Extension
Regulation Of Cell Shape
Regulation Of Cell Size
Positive Regulation Of Gene Expression
Protein Kinase A Signaling
Positive Regulation Of Cell Migration
Regulation Of Actin Filament Bundle Assembly
Regulation Of Rap Protein Signal Transduction
Negative Regulation Of Homotypic Cell-cell Adhesion
Negative Regulation Of GTPase Activity
Cellular Response To Platelet-derived Growth Factor Stimulus
Regulation Of GTPase Activity
Apical Protein Localization
Establishment Of Protein Localization
Negative Regulation Of Cell Size
Barbed-end Actin Filament Capping
Establishment Of Endothelial Barrier
Protein Localization To Plasma Membrane
Cellular Response To Thyroid Hormone Stimulus
Regulation Of Ruffle Assembly
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Organelle Assembly
Positive Regulation Of Protein Localization To Early Endosome
Positive Regulation Of Cellular Protein Catabolic Process
Negative Regulation Of Adherens Junction Organization
Positive Regulation Of Early Endosome To Late Endosome Transport
Pathways
Glycerophospholipid biosynthesis
Neutrophil degranulation
Recycling pathway of L1
Recycling pathway of L1
Drugs
Theophylline
1D-myo-inositol 1,4,5-trisphosphate
Diseases
GWAS
Blood protein levels (
30072576
29875488
28240269
)
Refractive error (
32231278
)
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI (age >50) (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Cognitive function (
24684796
)
Coronary artery disease (
32469254
)
Multiple sclerosis (
31604244
)
Interacting Genes
20 interacting genes:
ACTB
BCOR
BUB3
CCDC22
CPNE4
LHX6
LIG4
MAP2K1
MYCBP
PDCD6
PITPNM2
PPP5C
RDX
SKIL
SORBS3
SPTBN1
STK3
UBE2M
UBE2O
WTAP
20 interacting genes:
ABCC2
ARHGDIA
C1QTNF9
CALM1
CPNE1
CPNE2
CPNE4
DRD3
EZR
GNA13
ICAM2
ITGB2
L1CAM
LINC01554
PSME3
ROCK1
SLC9A3R1
SLC9A3R2
TSC1
VPS11
Entrez ID
8904
5962
HPRD ID
05014
01534
Ensembl ID
ENSG00000214078
ENSG00000137710
Uniprot IDs
B0QZ18
Q99829
B0YJ88
P35241
Q6PKD3
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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