RDX and CPNE2

Data Source:
HPRD (two hybrid)

		RDX	CPNE2
Description		radixin	copine 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Microvillus Adherens Junction Focal Adhesion Apical Plasma Membrane Lamellipodium Filopodium T-tubule Midbody Cortical Actin Cytoskeleton Cleavage Furrow Cell Tip Extracellular Exosome Cell Periphery	Nucleus Cytoplasm Plasma Membrane Extracellular Exosome
	Molecular Function	RNA Binding Actin Binding Protein Binding Cadherin Binding Protein Kinase A Binding ATPase Binding	Protein Binding Calcium-dependent Phospholipid Binding Metal Ion Binding
	Biological Process	Regulation Of Cell Shape Regulation Of Cell Size Positive Regulation Of Gene Expression Protein Kinase A Signaling Positive Regulation Of Cell Migration Regulation Of Actin Filament Bundle Assembly Regulation Of Rap Protein Signal Transduction Negative Regulation Of Homotypic Cell-cell Adhesion Negative Regulation Of GTPase Activity Cellular Response To Platelet-derived Growth Factor Stimulus Regulation Of GTPase Activity Apical Protein Localization Establishment Of Protein Localization Negative Regulation Of Cell Size Barbed-end Actin Filament Capping Establishment Of Endothelial Barrier Protein Localization To Plasma Membrane Cellular Response To Thyroid Hormone Stimulus Regulation Of Ruffle Assembly Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Organelle Assembly Positive Regulation Of Protein Localization To Early Endosome Positive Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Adherens Junction Organization Positive Regulation Of Early Endosome To Late Endosome Transport	Cellular Response To Calcium Ion
Pathways		Recycling pathway of L1 Recycling pathway of L1
Drugs		1D-myo-inositol 1,4,5-trisphosphate
Diseases
GWAS		Cognitive function ( 24684796) Coronary artery disease ( 32469254) Multiple sclerosis ( 31604244)
Interacting Genes		20 interacting genes: ABCC2 ARHGDIA C1QTNF9 CALM1 CPNE1 CPNE2 CPNE4 DRD3 EZR GNA13 ICAM2 ITGB2 L1CAM LINC01554 PSME3 ROCK1 SLC9A3R1 SLC9A3R2 TSC1 VPS11	28 interacting genes: ACTB ANXA7 BCOR CDKN1A CT55 EFHC2 GBP7 IKBKG KATNBL1 LNX1 MEI4 MEOX2 MYCBP NCKIPSD PDCD6 PICK1 PPP5C RDX REL SKIL SORBS3 TCF4 TERF2IP THAP4 TRIM27 UBA3 UBE2M UBE2O
Entrez ID		5962	221184
HPRD ID		01534	05015
Ensembl ID		ENSG00000137710	ENSG00000140848
Uniprot IDs		B0YJ88 P35241 Q6PKD3	Q96FN4
PDB IDs
Enriched GO Terms of Interacting Partners?
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