AOC3 and DARS2

Data Source:
BioGRID (two hybrid)

		AOC3	DARS2
Description		amine oxidase copper containing 3	aspartyl-tRNA synthetase 2, mitochondrial
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GO Annotations	Cellular Component	Cytoplasm Early Endosome Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Microvillus Cell Surface Integral Component Of Membrane	Nucleoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	Copper Ion Binding Calcium Ion Binding Protein Binding Primary Amine Oxidase Activity Identical Protein Binding Protein Heterodimerization Activity Quinone Binding Tryptamine:oxygen Oxidoreductase (deaminating) Activity Aminoacetone:oxygen Oxidoreductase(deaminating) Activity Aliphatic-amine Oxidase Activity Phenethylamine:oxygen Oxidoreductase (deaminating) Activity	TRNA Binding Aspartate-tRNA Ligase Activity Protein Binding ATP Binding Protein Homodimerization Activity Aspartate-tRNA(Asn) Ligase Activity
	Biological Process	Xenobiotic Metabolic Process Inflammatory Response Cell Adhesion Amine Metabolic Process Response To Antibiotic Negative Regulation Of Primary Amine Oxidase Activity	TRNA Aminoacylation For Protein Translation TRNA Aminoacylation Mitochondrial Asparaginyl-tRNA Aminoacylation
Pathways		Phase I - Functionalization of compounds	Mitochondrial tRNA aminoacylation
Drugs		Phenelzine Hydralazine 6-hydroxydopa quinone	Aspartic acid
Diseases			Leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation (LBSL)
GWAS			Hematocrit ( 32888494) Hemoglobin ( 32888494) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		13 interacting genes: ARL13B CLDN9 CPLX4 CREB3L1 DARS2 FNDC9 HSD17B13 LMNA MYBPC2 PRRG4 SGTA STX1A VAV1	15 interacting genes: AIMP2 ALDH18A1 AOC3 CDIPT COL8A2 CYB561 DPYSL5 EPHA8 FETUB KARS1 PLP2 THSD7B TMEM239 TSPAN33 UNC50
Entrez ID		8639	55157
HPRD ID		04770	07677
Ensembl ID		ENSG00000131471	ENSG00000117593
Uniprot IDs		Q16853 Q9UEU7	Q6PI48 Q9H9J7
PDB IDs		1PU4 1US1 2C10 2C11 2Y73 2Y74 3ALA 4BTW 4BTX 4BTY	4AH6
Enriched GO Terms of Interacting Partners?
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