DARS2 and UNC50

Data Source:
BioGRID (two hybrid)

		DARS2	UNC50
Description		aspartyl-tRNA synthetase 2, mitochondrial	unc-50 inner nuclear membrane RNA binding protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Matrix	Nuclear Inner Membrane Integral Component Of Golgi Membrane
	Molecular Function	TRNA Binding Aspartate-tRNA Ligase Activity Protein Binding ATP Binding Protein Homodimerization Activity Aspartate-tRNA(Asn) Ligase Activity	RNA Binding Protein Binding
	Biological Process	TRNA Aminoacylation For Protein Translation TRNA Aminoacylation Mitochondrial Asparaginyl-tRNA Aminoacylation	Transport Protein Transport
Pathways		Mitochondrial tRNA aminoacylation
Drugs		Aspartic acid
Diseases		Leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation (LBSL)
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)	Diverticular disease ( 30177863)
Interacting Genes		15 interacting genes: AIMP2 ALDH18A1 AOC3 CDIPT COL8A2 CYB561 DPYSL5 EPHA8 FETUB KARS1 PLP2 THSD7B TMEM239 TSPAN33 UNC50	33 interacting genes: AQP6 CLEC10A CLRN1 CREB3 DARS2 EBP ELOVL4 ERGIC3 FAM209A FCER1G FFAR2 FITM2 GPR152 GPX8 HSD17B11 HSD17B13 IFNGR2 KCNJ6 LMNA MFF MFSD14B MGST3 MTIF3 MUC1 REEP4 SAR1A SGPL1 SLC10A1 SLC10A6 TMED8 TMEM14B TMEM167B TMEM234
Entrez ID		55157	25972
HPRD ID		07677	18259
Ensembl ID		ENSG00000117593	ENSG00000115446
Uniprot IDs		Q6PI48 Q9H9J7	A0A0S2Z612 J3KQ47 Q53HI1
PDB IDs		4AH6
Enriched GO Terms of Interacting Partners?
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