DARS2 and FETUB

Data Source:
BioGRID (two hybrid)

		DARS2	FETUB
Description		aspartyl-tRNA synthetase 2, mitochondrial	fetuin B
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Matrix	Extracellular Region Extracellular Exosome
	Molecular Function	TRNA Binding Aspartate-tRNA Ligase Activity Protein Binding ATP Binding Protein Homodimerization Activity Aspartate-tRNA(Asn) Ligase Activity	Molecular_function Endopeptidase Inhibitor Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Metalloendopeptidase Inhibitor Activity
	Biological Process	TRNA Aminoacylation For Protein Translation TRNA Aminoacylation Mitochondrial Asparaginyl-tRNA Aminoacylation	Single Fertilization Binding Of Sperm To Zona Pellucida Biological_process Negative Regulation Of Endopeptidase Activity
Pathways		Mitochondrial tRNA aminoacylation
Drugs		Aspartic acid
Diseases		Leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation (LBSL)
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)	Activated partial thromboplastin time ( 22703881) Blood protein levels ( 28240269) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Neurological blood protein biomarker levels ( 31320639)
Interacting Genes		15 interacting genes: AIMP2 ALDH18A1 AOC3 CDIPT COL8A2 CYB561 DPYSL5 EPHA8 FETUB KARS1 PLP2 THSD7B TMEM239 TSPAN33 UNC50	8 interacting genes: CREB3L1 DARS2 EBP ERGIC3 HSD17B13 LMNA MTIF3 UBC
Entrez ID		55157	26998
HPRD ID		07677	09335
Ensembl ID		ENSG00000117593	ENSG00000090512
Uniprot IDs		Q6PI48 Q9H9J7	E9PG08 Q5J875 Q9UGM5
PDB IDs		4AH6	6SAZ
Enriched GO Terms of Interacting Partners?
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