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MFSD5 and TBXA2R
Data Source:
BioGRID
(two hybrid)
MFSD5
TBXA2R
Description
major facilitator superfamily domain containing 5
thromboxane A2 receptor
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Membrane
Integral Component Of Membrane
Acrosomal Vesicle
Plasma Membrane
Integral Component Of Plasma Membrane
Nuclear Speck
Molecular Function
Protein Binding
Molybdate Ion Transmembrane Transporter Activity
Thromboxane A2 Receptor Activity
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Biological Process
Molybdate Ion Transport
Inflammatory Response
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Response To Nutrient
Positive Regulation Of Blood Coagulation
Response To Testosterone
Thromboxane A2 Signaling Pathway
Response To Drug
Response To Ethanol
Positive Regulation Of Angiogenesis
Positive Regulation Of Blood Pressure
Positive Regulation Of Vasoconstriction
Positive Regulation Of Smooth Muscle Contraction
Regulation Of Catalytic Activity
Cellular Response To Lipopolysaccharide
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Pathways
Prostanoid ligand receptors
G alpha (q) signalling events
G alpha (12/13) signalling events
Thromboxane signalling through TP receptor
Drugs
Ridogrel
Seratrodast
Morniflumate
Diseases
GWAS
Interacting Genes
61 interacting genes:
ADGRE2
AQP6
ARL6IP1
BEST2
BLCAP
BTNL9
C2CD2L
CBARP
CCL4L2
CD40
CD79A
CLDN7
CLRN1
CREB3
CREB3L1
CYB5B
ERRFI1
FFAR2
FXYD3
GJA5
GLP1R
GOSR2
GPR101
GPR152
GPR25
GPR42
GPX8
HSD17B13
IGFBP5
IL27RA
KASH5
LAT
LHFPL5
LMNA
MMGT1
MUC1
PEX19
PGRMC2
PKMYT1
PLN
RNF144A
RNF19B
RTP2
SCN3B
SEC22B
SHISAL1
SLC10A6
SLC18A2
SLC39A9
SSMEM1
STATH
TBXA2R
TIMMDC1
TMEM128
TMEM130
TMEM14B
TMEM179B
TMEM203
TMEM237
XRN1
YIPF6
35 interacting genes:
ADIPOR1
ARL6IP6
C5orf46
EMP1
GJB2
GNA11
GNA12
GNA13
GNAI2
GNAQ
GNAS
GNB1
GNG2
GPRASP1
GRK5
GRK6
MFSD5
MS4A13
NME2
NOX1
PRDX4
PRKCA
PSMA7
PSME3
PTGIR
RAB11A
RACK1
RAF1
RPGRIP1L
SLC35B4
SLC41A1
TM4SF4
VRK2
YWHAZ
ZDHHC15
Entrez ID
84975
6915
HPRD ID
14416
01768
Ensembl ID
ENSG00000182544
ENSG00000006638
Uniprot IDs
Q6N075
P21731
Q05C92
Q0VAB0
PDB IDs
1LBN
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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