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TBXA2R and EMP1
Data Source:
BioGRID
(two hybrid)
TBXA2R
EMP1
Description
thromboxane A2 receptor
epithelial membrane protein 1
Image
No pdb structure
GO Annotations
Cellular Component
Acrosomal Vesicle
Plasma Membrane
Integral Component Of Plasma Membrane
Nuclear Speck
Plasma Membrane
Integral Component Of Membrane
Molecular Function
Thromboxane A2 Receptor Activity
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Protein Binding
Biological Process
Inflammatory Response
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Response To Nutrient
Positive Regulation Of Blood Coagulation
Response To Testosterone
Thromboxane A2 Signaling Pathway
Response To Drug
Response To Ethanol
Positive Regulation Of Angiogenesis
Positive Regulation Of Blood Pressure
Positive Regulation Of Vasoconstriction
Positive Regulation Of Smooth Muscle Contraction
Regulation Of Catalytic Activity
Cellular Response To Lipopolysaccharide
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Cell Death
Epidermis Development
Bleb Assembly
Pathways
Prostanoid ligand receptors
G alpha (q) signalling events
G alpha (12/13) signalling events
Thromboxane signalling through TP receptor
Drugs
Ridogrel
Seratrodast
Morniflumate
Diseases
GWAS
Coronary artery calcification (
23870195
)
Degraded stimulus continuous performance test score (
31596458
)
Estimated glomerular filtration rate after 1 year in renal transplantation (donor effect) (
30920136
)
Heel bone mineral density (
30598549
28869591
)
Household income (MTAG) (
31844048
)
Refractive error (
32231278
)
Serum albumin level (
29403010
)
Interacting Genes
35 interacting genes:
ADIPOR1
ARL6IP6
C5orf46
EMP1
GJB2
GNA11
GNA12
GNA13
GNAI2
GNAQ
GNAS
GNB1
GNG2
GPRASP1
GRK5
GRK6
MFSD5
MS4A13
NME2
NOX1
PRDX4
PRKCA
PSMA7
PSME3
PTGIR
RAB11A
RACK1
RAF1
RPGRIP1L
SLC35B4
SLC41A1
TM4SF4
VRK2
YWHAZ
ZDHHC15
61 interacting genes:
ANK1
ANKS6
APOL2
AQP6
ARL13B
ARL6IP1
ASGR2
ATP6V0B
ATP6V0E1
BTN2A2
CCR5
CD37
CD3G
CD53
CD79A
CEP70
CLDN9
CORIN
CXCR2
EBP
EDA
EHHADH
ERGIC3
FFAR2
GIMAP5
GPR42
GPRC5D
HTR2C
ISLR2
JPH1
KLRC1
LAPTM4B
LEPROTL1
LHFPL5
LPAR6
LRRC3B
LSMEM2
MAL
MALL
MS4A7
OPRM1
PLEKHB2
PMP22
RABAC1
RPRM
SERTM1
SMIM3
SPACA1
STOM
SYNE4
TBXA2R
TEX264
TLCD4
TMEM114
TMEM160
TMEM218
TMEM239
TMEM262
TMEM31
TMEM9
TSPO2
Entrez ID
6915
2012
HPRD ID
01768
11892
Ensembl ID
ENSG00000006638
ENSG00000134531
Uniprot IDs
P21731
Q05C92
Q0VAB0
A0A024RAT0
P54849
PDB IDs
1LBN
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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