MFSD5 and ADGRE2

Data Source:
BioGRID (two hybrid)

		MFSD5	ADGRE2
Description		major facilitator superfamily domain containing 5	adhesion G protein-coupled receptor E2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Leading Edge Membrane Ruffle Membrane
	Molecular Function	Protein Binding Molybdate Ion Transmembrane Transporter Activity	G Protein-coupled Receptor Activity Calcium Ion Binding Protein Binding Chondroitin Sulfate Binding
	Biological Process	Molybdate Ion Transport	Inflammatory Response Cell Adhesion Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell Migration Regulation Of Mast Cell Degranulation Granulocyte Chemotaxis
Pathways			Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Plasma androstenedione levels in resected early stage-receptor positive breast cancer ( 28429243)
Interacting Genes		61 interacting genes: ADGRE2 AQP6 ARL6IP1 BEST2 BLCAP BTNL9 C2CD2L CBARP CCL4L2 CD40 CD79A CLDN7 CLRN1 CREB3 CREB3L1 CYB5B ERRFI1 FFAR2 FXYD3 GJA5 GLP1R GOSR2 GPR101 GPR152 GPR25 GPR42 GPX8 HSD17B13 IGFBP5 IL27RA KASH5 LAT LHFPL5 LMNA MMGT1 MUC1 PEX19 PGRMC2 PKMYT1 PLN RNF144A RNF19B RTP2 SCN3B SEC22B SHISAL1 SLC10A6 SLC18A2 SLC39A9 SSMEM1 STATH TBXA2R TIMMDC1 TMEM128 TMEM130 TMEM14B TMEM179B TMEM203 TMEM237 XRN1 YIPF6	19 interacting genes: AQP6 BIK CCDC107 CREB3L1 ELOVL4 ELOVL7 FAM209A FCER1G HSD17B13 KIR2DL3 LMNA MARCHF6 MFSD5 MMGT1 MTERF3 SAR1A SLC7A14 TLCD4 TMEM80
Entrez ID		84975	30817
HPRD ID		14416	07308
Ensembl ID		ENSG00000182544	ENSG00000127507
Uniprot IDs		Q6N075	A0JNV7 Q9UHX3
PDB IDs			2BO2 2BOU 2BOX
Enriched GO Terms of Interacting Partners?
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