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TBXA2R and TM4SF4
Data Source:
BioGRID
(two hybrid)
TBXA2R
TM4SF4
Description
thromboxane A2 receptor
transmembrane 4 L six family member 4
Image
No pdb structure
GO Annotations
Cellular Component
Acrosomal Vesicle
Plasma Membrane
Integral Component Of Plasma Membrane
Nuclear Speck
Integral Component Of Membrane
Molecular Function
Thromboxane A2 Receptor Activity
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Protein Binding
Biological Process
Inflammatory Response
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Response To Nutrient
Positive Regulation Of Blood Coagulation
Response To Testosterone
Thromboxane A2 Signaling Pathway
Response To Drug
Response To Ethanol
Positive Regulation Of Angiogenesis
Positive Regulation Of Blood Pressure
Positive Regulation Of Vasoconstriction
Positive Regulation Of Smooth Muscle Contraction
Regulation Of Catalytic Activity
Cellular Response To Lipopolysaccharide
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Tissue Regeneration
Pathways
Prostanoid ligand receptors
G alpha (q) signalling events
G alpha (12/13) signalling events
Thromboxane signalling through TP receptor
Drugs
Ridogrel
Seratrodast
Morniflumate
Diseases
GWAS
Alanine transaminase levels (
29403010
)
Gallstone disease (
30504769
27094239
)
Gamma glutamyl transferase levels (
29403010
)
Ischemic stroke (large artery atherosclerosis) (
29531354
)
Serum uric acid levels (
30993211
)
Thyroid stimulating hormone levels (
30367059
32769997
)
Urate levels (
31578528
)
Interacting Genes
35 interacting genes:
ADIPOR1
ARL6IP6
C5orf46
EMP1
GJB2
GNA11
GNA12
GNA13
GNAI2
GNAQ
GNAS
GNB1
GNG2
GPRASP1
GRK5
GRK6
MFSD5
MS4A13
NME2
NOX1
PRDX4
PRKCA
PSMA7
PSME3
PTGIR
RAB11A
RACK1
RAF1
RPGRIP1L
SLC35B4
SLC41A1
TM4SF4
VRK2
YWHAZ
ZDHHC15
22 interacting genes:
APH1B
CD79A
CLEC17A
CMTM2
CREB3
ERGIC3
FATE1
FFAR2
GJB1
GJB4
GJB5
GLP1R
GPR101
GPR37L1
GPR42
GPX8
KCNK5
LHFPL5
OPRM1
SLC10A6
TBXA2R
TMEM14B
Entrez ID
6915
7104
HPRD ID
01768
07585
Ensembl ID
ENSG00000006638
ENSG00000169903
Uniprot IDs
P21731
Q05C92
Q0VAB0
P48230
PDB IDs
1LBN
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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