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TBXA2R and C5orf46
Data Source:
BioGRID
(two hybrid)
TBXA2R
C5orf46
Description
thromboxane A2 receptor
chromosome 5 open reading frame 46
Image
No pdb structure
GO Annotations
Cellular Component
Acrosomal Vesicle
Plasma Membrane
Integral Component Of Plasma Membrane
Nuclear Speck
Extracellular Exosome
Molecular Function
Thromboxane A2 Receptor Activity
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Molecular_function
Protein Binding
Biological Process
Inflammatory Response
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Response To Nutrient
Positive Regulation Of Blood Coagulation
Response To Testosterone
Thromboxane A2 Signaling Pathway
Response To Drug
Response To Ethanol
Positive Regulation Of Angiogenesis
Positive Regulation Of Blood Pressure
Positive Regulation Of Vasoconstriction
Positive Regulation Of Smooth Muscle Contraction
Regulation Of Catalytic Activity
Cellular Response To Lipopolysaccharide
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Biological_process
Pathways
Prostanoid ligand receptors
G alpha (q) signalling events
G alpha (12/13) signalling events
Thromboxane signalling through TP receptor
Drugs
Ridogrel
Seratrodast
Morniflumate
Diseases
GWAS
Alcoholic chronic pancreatitis (
28754779
)
Interacting Genes
35 interacting genes:
ADIPOR1
ARL6IP6
C5orf46
EMP1
GJB2
GNA11
GNA12
GNA13
GNAI2
GNAQ
GNAS
GNB1
GNG2
GPRASP1
GRK5
GRK6
MFSD5
MS4A13
NME2
NOX1
PRDX4
PRKCA
PSMA7
PSME3
PTGIR
RAB11A
RACK1
RAF1
RPGRIP1L
SLC35B4
SLC41A1
TM4SF4
VRK2
YWHAZ
ZDHHC15
12 interacting genes:
AQP6
EBP
FAM210B
LHFPL5
PEX12
RUSF1
SGTA
SGTB
SLC30A2
TBXA2R
TIMMDC1
TMEM80
Entrez ID
6915
389336
HPRD ID
01768
14491
Ensembl ID
ENSG00000006638
ENSG00000178776
Uniprot IDs
P21731
Q05C92
Q0VAB0
Q6UWT4
PDB IDs
1LBN
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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