Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
TBXA2R and ZDHHC15
Data Source:
BioGRID
(two hybrid)
TBXA2R
ZDHHC15
Description
thromboxane A2 receptor
zinc finger DHHC-type palmitoyltransferase 15
Image
No pdb structure
GO Annotations
Cellular Component
Acrosomal Vesicle
Plasma Membrane
Integral Component Of Plasma Membrane
Nuclear Speck
Golgi Membrane
Endoplasmic Reticulum
Golgi Apparatus
Postsynaptic Density
Integral Component Of Golgi Membrane
Postsynapse
Molecular Function
Thromboxane A2 Receptor Activity
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Protein Binding
Zinc Ion Binding
Palmitoyltransferase Activity
Protein-cysteine S-palmitoyltransferase Activity
Biological Process
Inflammatory Response
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Response To Nutrient
Positive Regulation Of Blood Coagulation
Response To Testosterone
Thromboxane A2 Signaling Pathway
Response To Drug
Response To Ethanol
Positive Regulation Of Angiogenesis
Positive Regulation Of Blood Pressure
Positive Regulation Of Vasoconstriction
Positive Regulation Of Smooth Muscle Contraction
Regulation Of Catalytic Activity
Cellular Response To Lipopolysaccharide
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Protein Targeting To Membrane
Synaptic Vesicle Maturation
Protein Phosphopantetheinylation
Peptidyl-L-cysteine S-palmitoylation
Protein Palmitoylation
Regulation Of Dendritic Spine Morphogenesis
Protein Localization To Postsynapse
Protein Localization To Membrane
Protein Targeting To Golgi Apparatus
Positive Regulation Of Dendrite Development
Pathways
Prostanoid ligand receptors
G alpha (q) signalling events
G alpha (12/13) signalling events
Thromboxane signalling through TP receptor
Drugs
Ridogrel
Seratrodast
Morniflumate
Diseases
Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
GWAS
Interacting Genes
35 interacting genes:
ADIPOR1
ARL6IP6
C5orf46
EMP1
GJB2
GNA11
GNA12
GNA13
GNAI2
GNAQ
GNAS
GNB1
GNG2
GPRASP1
GRK5
GRK6
MFSD5
MS4A13
NME2
NOX1
PRDX4
PRKCA
PSMA7
PSME3
PTGIR
RAB11A
RACK1
RAF1
RPGRIP1L
SLC35B4
SLC41A1
TM4SF4
VRK2
YWHAZ
ZDHHC15
48 interacting genes:
ADCYAP1R1
ARL13B
BNIP3
C14orf180
CD79A
CELA2B
CERCAM
CLEC10A
CLRN1
CREB3L1
CYB5R3
DHRSX
ERGIC3
FAM241B
GIMAP1
GOLGA7B
GPR152
LEMD1
LEPROTL1
LHFPL5
LMNA
LSMEM1
MCEMP1
MTIF3
ORMDL1
ORMDL2
PEX16
PLLP
PRAF2
PVR
RUSF1
SLC10A6
SMIM1
SNORC
STX3
TBXA2R
TMEFF2
TMEM120B
TMEM128
TMEM14C
TMEM222
TMEM42
TMEM52B
TNFRSF10B
TSNARE1
TUFM
VAPB
YIPF4
Entrez ID
6915
158866
HPRD ID
01768
06758
Ensembl ID
ENSG00000006638
ENSG00000102383
Uniprot IDs
P21731
Q05C92
Q0VAB0
B3KY34
Q96MV8
PDB IDs
1LBN
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?