C2orf88 and CENPP

Data Source:
BioGRID (two hybrid)

		C2orf88	CENPP
Description		chromosome 2 open reading frame 88	centromere protein P
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane	Chromosome, Centromeric Region Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function	Protein Binding Protein Kinase A Regulatory Subunit Binding	Protein Binding
	Biological Process		CENP-A Containing Nucleosome Assembly
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Blood protein levels ( 29875488) End-stage renal disease ( 29885931) HDL cholesterol levels ( 32203549) Height ( 28552196 31562340) Malaria ( 31844061) Pulse pressure ( 30578418) Systolic blood pressure ( 30224653 30578418) Triglyceride levels ( 32203549) Urate levels ( 31578528)
Interacting Genes		11 interacting genes: ARMC7 BATF2 CENPP FBXO7 MYOD1 NFKBIL1 PRKAR1A PRKAR2B RALGPS1 TDP2 ZMIZ2	27 interacting genes: ATP6V0D2 BACH2 C2orf88 CCDC33 CCDC85B CENPO CEP44 GOLGA2 HAUS1 KIAA1328 KLC3 LMNA MBD3 NHLH1 NTAQ1 PKNOX2 POLR3K RNF126 RPIA SERTAD3 STXBP1 SYCE1L TEX11 TOX2 USHBP1 ZNF341 ZNF765
Entrez ID		84281	401541
HPRD ID		14436	17989
Ensembl ID		ENSG00000187699	ENSG00000188312
Uniprot IDs		Q9BSF0	Q6IPU0 Q7Z672
PDB IDs		5HVZ
Enriched GO Terms of Interacting Partners?
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