ARL6 and ARL6IP5

Data Source:
HPRD (two hybrid)

		ARL6	ARL6IP5
Description		ADP ribosylation factor like GTPase 6	ADP ribosylation factor like GTPase 6 interacting protein 5
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Axonemal Microtubule Plasma Membrane Cilium Axoneme Membrane Membrane Coat Extracellular Exosome	Endoplasmic Reticulum Membrane Cytoskeleton Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Phospholipid Binding Metal Ion Binding	Molecular_function Protein Binding
	Biological Process	Protein Targeting To Membrane Intracellular Protein Transport Determination Of Left/right Symmetry Visual Perception Wnt Signaling Pathway Vesicle-mediated Transport Melanosome Transport Protein Polymerization Cilium Assembly Protein Localization To Cilium	Negative Regulation Of L-glutamate Import Across Plasma Membrane Glutathione Metabolic Process Learning Or Memory Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Negative Regulation Of Mitochondrial Membrane Potential L-glutamate Transmembrane Transport Positive Regulation Of Stress-activated MAPK Cascade Neuron Death In Response To Oxidative Stress Positive Regulation Of Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Transport Protein Localization To Plasma Membrane L-glutamate Import Across Plasma Membrane
Pathways		BBSome-mediated cargo-targeting to cilium	Glutamate Neurotransmitter Release Cycle
Drugs
Diseases		Bardet-Biedl syndrome (BBS) Retinitis pigmentosa (RP)
GWAS		Male infertility ( 19478329)	Urate levels ( 31578528)
Interacting Genes		6 interacting genes: ARL6IP1 ARL6IP4 ARL6IP5 ARL6IP6 ATL2 SEC61B	9 interacting genes: ARL6 CCR2 CCR5 CLN8 KRAS NOTCH1 PRAF2 SLC1A1 VKORC1
Entrez ID		84100	10550
HPRD ID		10588	09303
Ensembl ID		ENSG00000113966	ENSG00000144746
Uniprot IDs		Q9H0F7	A0A024R371 O75915
PDB IDs		2H57
Enriched GO Terms of Interacting Partners?
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