ARL6IP5 and PRAF2

Data Source:
BioGRID (proximity labelling technology)
HPRD (in vivo)

		ARL6IP5	PRAF2
Description		ADP ribosylation factor like GTPase 6 interacting protein 5	PRA1 domain family member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Cytoskeleton Plasma Membrane Membrane Integral Component Of Membrane	Endosome Membrane Membrane Integral Component Of Membrane
	Molecular Function	Molecular_function Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of L-glutamate Import Across Plasma Membrane Glutathione Metabolic Process Learning Or Memory Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Negative Regulation Of Mitochondrial Membrane Potential L-glutamate Transmembrane Transport Positive Regulation Of Stress-activated MAPK Cascade Neuron Death In Response To Oxidative Stress Positive Regulation Of Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Transport Protein Localization To Plasma Membrane L-glutamate Import Across Plasma Membrane	Protein Transport L-glutamate Transmembrane Transport
Pathways		Glutamate Neurotransmitter Release Cycle
Drugs
Diseases
GWAS		Urate levels ( 31578528)
Interacting Genes		9 interacting genes: ARL6 CCR2 CCR5 CLN8 KRAS NOTCH1 PRAF2 SLC1A1 VKORC1	26 interacting genes: ABHD16A ADGRD1 AGR3 AQP6 ARL6IP5 CCR5 CD79A CIAO2A CLEC10A EBAG9 GJA5 GJA8 GPR152 HIBADH HSD17B11 MCEMP1 MIEF1 NDRG4 REEP4 RETREG3 RNF5 SLC10A6 TLCD4 TMEM14B TMX2 ZDHHC15
Entrez ID		10550	11230
HPRD ID		09303	06596
Ensembl ID		ENSG00000144746	ENSG00000243279
Uniprot IDs		A0A024R371 O75915	A0A024QZ22 O60831
PDB IDs
Enriched GO Terms of Interacting Partners?
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