ARL6IP5 and ARL6

Data Source:
HPRD (two hybrid)

		ARL6IP5	ARL6
Description		ADP ribosylation factor like GTPase 6 interacting protein 5	ADP ribosylation factor like GTPase 6
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Cytoskeleton Plasma Membrane Membrane Integral Component Of Membrane	Cytoplasm Axonemal Microtubule Plasma Membrane Cilium Axoneme Membrane Membrane Coat Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding	GTPase Activity Protein Binding GTP Binding Phospholipid Binding Metal Ion Binding
	Biological Process	Negative Regulation Of L-glutamate Import Across Plasma Membrane Glutathione Metabolic Process Learning Or Memory Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Negative Regulation Of Mitochondrial Membrane Potential L-glutamate Transmembrane Transport Positive Regulation Of Stress-activated MAPK Cascade Neuron Death In Response To Oxidative Stress Positive Regulation Of Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Transport Protein Localization To Plasma Membrane L-glutamate Import Across Plasma Membrane	Protein Targeting To Membrane Intracellular Protein Transport Determination Of Left/right Symmetry Visual Perception Wnt Signaling Pathway Vesicle-mediated Transport Melanosome Transport Protein Polymerization Cilium Assembly Protein Localization To Cilium
Pathways		Glutamate Neurotransmitter Release Cycle	BBSome-mediated cargo-targeting to cilium
Drugs
Diseases			Bardet-Biedl syndrome (BBS) Retinitis pigmentosa (RP)
GWAS		Urate levels ( 31578528)	Male infertility ( 19478329)
Interacting Genes		9 interacting genes: ARL6 CCR2 CCR5 CLN8 KRAS NOTCH1 PRAF2 SLC1A1 VKORC1	6 interacting genes: ARL6IP1 ARL6IP4 ARL6IP5 ARL6IP6 ATL2 SEC61B
Entrez ID		10550	84100
HPRD ID		09303	10588
Ensembl ID		ENSG00000144746	ENSG00000113966
Uniprot IDs		A0A024R371 O75915	Q9H0F7
PDB IDs			2H57
Enriched GO Terms of Interacting Partners?
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