SPOP and ZCCHC12

		SPOP	ZCCHC12
Description		speckle type BTB/POZ protein	zinc finger CCHC-type containing 12
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Cul3-RING Ubiquitin Ligase Complex	Nucleus
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	Nucleic Acid Binding Protein Binding Zinc Ion Binding
	Biological Process	Protein Polyubiquitination Regulation Of Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		Hedgehog 'on' state
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Interacting Genes		66 interacting genes: AEN AMOTL2 AR BRD2 BRD3 BRMS1 CACUL1 CBX4 CCNE1 CDK4 CHAF1A CHD3 CREB5 CTDSPL2 CUL3 DDIT3 DHX15 DPPA2 EGLN2 ERF ERG FAF1 GATAD2A GCC1 GCC2 GIT2 GLI2 GMEB1 HCST HMGCS1 INF2 IRF1 KPNA5 LRCH4 MACROH2A1 MRE11 MYD88 NANOG NCOA3 NUDCD3 PDX1 PIAS1 PIAS3 RANBP9 RBFOX2 RBPJ RPRD2 RTN3 RXRB SETD2 SRRM1 SUMO1 TCOF1 TOPORS TRAF1 TRAF6 UBE2D1 UBE2D2 UBE2E3 UBE2I UBE2L3 VPS9D1-AS1 YWHAG ZBTB16 ZCCHC12 ZMYND8	26 interacting genes: ABHD5 APP APPBP2 ATP6V0C CD207 FADD FATE1 KPNA3 LMO1 MAGEA11 MCRS1 MX1 PNMA1 RNF40 RUSF1 SPOP STX2 SUMO1 SUMO2 SUMO3 TADA2A TFCP2 TMEM43 TMEM79 TNF UBE2I
Entrez ID		8405	170261
HPRD ID		16004	06616
Ensembl ID		ENSG00000121067	ENSG00000174460
Uniprot IDs		O43791	Q6PEW1
PDB IDs		2CR2 3HQH 3HQI 3HQL 3HQM 3HSV 3HTM 3HU6 3IVB 3IVQ 3IVV 4EOZ 4HS2 4J8Z 4O1V 6F8F 6F8G 6I41 6I5P 6I68 6I7A
Enriched GO Terms of Interacting Partners?
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