SPOP and NUDCD3

Data Source:
BioGRID (two hybrid)

		SPOP	NUDCD3
Description		speckle type BTB/POZ protein	NudC domain containing 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Cul3-RING Ubiquitin Ligase Complex	Cytoplasm Cytoplasmic Dynein Complex
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	Protein Binding Unfolded Protein Binding
	Biological Process	Protein Polyubiquitination Regulation Of Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Protein Folding Cilium Assembly Protein Localization To Pericentriolar Material
Pathways		Hedgehog 'on' state
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)	Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321) Iris color (b* coordinate) ( 30895295)
Interacting Genes		66 interacting genes: AEN AMOTL2 AR BRD2 BRD3 BRMS1 CACUL1 CBX4 CCNE1 CDK4 CHAF1A CHD3 CREB5 CTDSPL2 CUL3 DDIT3 DHX15 DPPA2 EGLN2 ERF ERG FAF1 GATAD2A GCC1 GCC2 GIT2 GLI2 GMEB1 HCST HMGCS1 INF2 IRF1 KPNA5 LRCH4 MACROH2A1 MRE11 MYD88 NANOG NCOA3 NUDCD3 PDX1 PIAS1 PIAS3 RANBP9 RBFOX2 RBPJ RPRD2 RTN3 RXRB SETD2 SRRM1 SUMO1 TCOF1 TOPORS TRAF1 TRAF6 UBE2D1 UBE2D2 UBE2E3 UBE2I UBE2L3 VPS9D1-AS1 YWHAG ZBTB16 ZCCHC12 ZMYND8	5 interacting genes: CCNDBP1 KRTAP10-3 KRTAP10-7 SPOP UBE2I
Entrez ID		8405	23386
HPRD ID		16004	13831
Ensembl ID		ENSG00000121067	ENSG00000015676
Uniprot IDs		O43791	Q8IVD9
PDB IDs		2CR2 3HQH 3HQI 3HQL 3HQM 3HSV 3HTM 3HU6 3IVB 3IVQ 3IVV 4EOZ 4HS2 4J8Z 4O1V 6F8F 6F8G 6I41 6I5P 6I68 6I7A	1WGV
Enriched GO Terms of Interacting Partners?
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