ZCCHC12 and ATP6V0C

Data Source:
BioGRID (two hybrid)

		ZCCHC12	ATP6V0C
Description		zinc finger CCHC-type containing 12	ATPase H+ transporting V0 subunit c
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Lysosomal Membrane Plasma Membrane Focal Adhesion Endosome Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Azurophil Granule Membrane Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Nucleic Acid Binding Protein Binding Zinc Ion Binding	Protein Binding Ubiquitin Protein Ligase Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process		Insulin Receptor Signaling Pathway ATP Synthesis Coupled Proton Transport Viral Process Regulation Of Macroautophagy Positive Regulation Of Wnt Signaling Pathway Transferrin Transport Ion Transmembrane Transport Neutrophil Degranulation Phagosome Acidification Proton Transmembrane Transport
Pathways			ROS and RNS production in phagocytes Neutrophil degranulation Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS
Interacting Genes		26 interacting genes: ABHD5 APP APPBP2 ATP6V0C CD207 FADD FATE1 KPNA3 LMO1 MAGEA11 MCRS1 MX1 PNMA1 RNF40 RUSF1 SPOP STX2 SUMO1 SUMO2 SUMO3 TADA2A TFCP2 TMEM43 TMEM79 TNF UBE2I	53 interacting genes: AQP6 ARF6 ASGR2 CD53 CD69 CD79A CERS2 CLEC14A CLEC17A CLEC2D CLIC1 CPLX4 CREB3 DNAJC1 DRD2 EDA EDA2R ERBB2 ERH EVI2A FAM210B FFAR2 GPR152 GPR25 GPR42 HSD17B13 HTR2C KLRC1 LMNA LRRC25 MARK3 MCEMP1 MDFI MSR1 NIPAL3 OPRM1 PDCD1LG2 PI16 PSMA3 RETREG3 SCN3B SLC35E3 SLC7A1 SMIM3 SPACA1 SSMEM1 STOM SUSD3 TMEM139 TMEM31 TMEM9 VSIR ZCCHC12
Entrez ID		170261	527
HPRD ID		06616	00162
Ensembl ID		ENSG00000174460	ENSG00000185883
Uniprot IDs		Q6PEW1	P27449
PDB IDs
Enriched GO Terms of Interacting Partners?
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