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ZCCHC12 and SPOP
Data Source:
BioGRID
(two hybrid)
ZCCHC12
SPOP
Description
zinc finger CCHC-type containing 12
speckle type BTB/POZ protein
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Speck
Cul3-RING Ubiquitin Ligase Complex
Molecular Function
Nucleic Acid Binding
Protein Binding
Zinc Ion Binding
Protein Binding
Ubiquitin Protein Ligase Binding
Biological Process
Protein Polyubiquitination
Regulation Of Proteolysis
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways
Hedgehog 'on' state
Drugs
Diseases
GWAS
Prostate cancer (
23535732
)
Interacting Genes
26 interacting genes:
ABHD5
APP
APPBP2
ATP6V0C
CD207
FADD
FATE1
KPNA3
LMO1
MAGEA11
MCRS1
MX1
PNMA1
RNF40
RUSF1
SPOP
STX2
SUMO1
SUMO2
SUMO3
TADA2A
TFCP2
TMEM43
TMEM79
TNF
UBE2I
66 interacting genes:
AEN
AMOTL2
AR
BRD2
BRD3
BRMS1
CACUL1
CBX4
CCNE1
CDK4
CHAF1A
CHD3
CREB5
CTDSPL2
CUL3
DDIT3
DHX15
DPPA2
EGLN2
ERF
ERG
FAF1
GATAD2A
GCC1
GCC2
GIT2
GLI2
GMEB1
HCST
HMGCS1
INF2
IRF1
KPNA5
LRCH4
MACROH2A1
MRE11
MYD88
NANOG
NCOA3
NUDCD3
PDX1
PIAS1
PIAS3
RANBP9
RBFOX2
RBPJ
RPRD2
RTN3
RXRB
SETD2
SRRM1
SUMO1
TCOF1
TOPORS
TRAF1
TRAF6
UBE2D1
UBE2D2
UBE2E3
UBE2I
UBE2L3
VPS9D1-AS1
YWHAG
ZBTB16
ZCCHC12
ZMYND8
Entrez ID
170261
8405
HPRD ID
06616
16004
Ensembl ID
ENSG00000174460
ENSG00000121067
Uniprot IDs
Q6PEW1
O43791
PDB IDs
2CR2
3HQH
3HQI
3HQL
3HQM
3HSV
3HTM
3HU6
3IVB
3IVQ
3IVV
4EOZ
4HS2
4J8Z
4O1V
6F8F
6F8G
6I41
6I5P
6I68
6I7A
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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