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SPRY4 and TNS2
Data Source:
BioGRID
(two hybrid)
SPRY4
TNS2
Description
sprouty RTK signaling antagonist 4
tensin 2
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Focal Adhesion
Ruffle Membrane
Plasma Membrane
Focal Adhesion
Molecular Function
Protein Kinase Inhibitor Activity
Protein Binding
Protein Tyrosine Phosphatase Activity
Protein Binding
Kinase Binding
Identical Protein Binding
Metal Ion Binding
Biological Process
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Negative Regulation Of MAP Kinase Activity
Negative Regulation Of Ras Protein Signal Transduction
Animal Organ Development
Negative Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Substrate Adhesion-dependent Cell Spreading
Kidney Development
Negative Regulation Of Cell Population Proliferation
Response To Muscle Activity
Cellular Homeostasis
Collagen Metabolic Process
Multicellular Organism Growth
Peptidyl-tyrosine Dephosphorylation
Intracellular Signal Transduction
Negative Regulation Of Insulin Receptor Signaling Pathway
Multicellular Organismal Homeostasis
Pathways
Drugs
Diseases
GWAS
Asthma (
31959851
29273806
)
Body mass index (
28552196
)
Erosive tooth wear (severe vs non-severe) (
29898447
)
Erosive tooth wear (severe vs none or mild) (
29898447
)
Gut microbiota (bacterial taxa) (
27723756
)
Height (
31562340
)
Inflammatory bowel disease (
23128233
)
Physiological traits (
31902109
)
Systolic blood pressure (
30578418
)
Testicular germ cell cancer (
20543847
)
Testicular germ cell tumor (
19483681
28604728
28604732
23666239
23666240
)
Interacting Genes
17 interacting genes:
ADAM12
COL8A1
CREB5
EFEMP2
FHL2
HOXA1
KLHL38
KRTAP5-11
NUTF2
OTX1
POU4F2
RAF1
RIN3
TESK1
TNS2
VENTX
ZDHHC17
150 interacting genes:
ADCK5
AMMECR1
AP1S2
AQP1
ARID5A
ASB3
AXL
BAHD1
BLZF1
BRCA1
C11orf87
C1orf94
CATSPER1
CCDC33
CNNM3
COX6B2
CPSF7
CRX
CSNK1E
CTSZ
DCAF11
DCAF8
DDIT4L
DLC1
DOK3
DZIP1
DZIP3
EGFR
ENKD1
EPB41L4A
EPDR1
EPS8L2
ERBB2
ERBB3
ERBB4
FABP7
FAM114A1
FAM228A
FASLG
FGF21
FGFR1
FOXO1
GATA1
GBA3
GFI1B
HOXA1
HOXB9
HOXC8
HUWE1
ID2
IHO1
INO80B
ITGB3
ITGB5
ITGB7
KCTD9
KIF1A
KIT
KPRP
KRT76
KRTAP1-3
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP11-1
KRTAP12-2
KRTAP12-3
KRTAP13-1
KRTAP13-2
KRTAP23-1
KRTAP3-1
KRTAP4-4
KRTAP6-3
LASP1
LPXN
LUZP4
MET
MGAT5B
MPEG1
MT2A
MTDH
MYBPHL
MYH7B
MYPOP
NBPF19
NMU
NOTCH2NLA
NT5C
NUBP2
OBSL1
OTX1
PATZ1
PER1
PHF1
PIN1
PKP1
PLB1
PLK3
PLSCR3
POLR1H
POLR3F
PRR22
RAMAC
RBAK
RBPMS
REEP6
REL
RFT1
RNF6
SDCCAG8
SERTAD2
SH2B3
SHFL
SOCS7
SORBS3
SPATA12
SPRY2
SPRY4
SUSD2
SUV39H1
TBC1D16
TCP10L
TEKT3
TEKT5
TENT5A
TENT5B
TFAP2D
TLE5
TM4SF19
TRIM8
TSC1
TWSG1
USP54
WAC
WDFY3
ZCCHC14
ZIM2
ZNF134
ZNF205
ZNF250
ZNF417
ZNF497
ZNF575
ZNF586
ZNF587
ZNF648
ZNF655
ZNF688
ZNF837
Entrez ID
81848
23371
HPRD ID
10466
16256
Ensembl ID
ENSG00000187678
ENSG00000111077
Uniprot IDs
A0A0C4DFS6
Q9C004
A0A024RB48
Q63HR2
PDB IDs
3BUN
2DKQ
2KNO
2L6K
2LOZ
3HQC
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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