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TNS2 and CTSZ
Data Source:
BioGRID
(two hybrid)
TNS2
CTSZ
Description
tensin 2
cathepsin Z
Image
GO Annotations
Cellular Component
Plasma Membrane
Focal Adhesion
Golgi Membrane
Extracellular Region
Extracellular Space
Lysosome
Endoplasmic Reticulum
Endoplasmic Reticulum Lumen
Plasma Membrane
COPII-coated ER To Golgi Transport Vesicle
Cytoplasmic Vesicle
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Specific Granule Lumen
Collagen-containing Extracellular Matrix
Extracellular Exosome
Cell Cortex Region
Ficolin-1-rich Granule Lumen
Molecular Function
Protein Tyrosine Phosphatase Activity
Protein Binding
Kinase Binding
Identical Protein Binding
Metal Ion Binding
Carboxypeptidase Activity
Cysteine-type Endopeptidase Activity
Protein Binding
Cysteine-type Peptidase Activity
Biological Process
Kidney Development
Negative Regulation Of Cell Population Proliferation
Response To Muscle Activity
Cellular Homeostasis
Collagen Metabolic Process
Multicellular Organism Growth
Peptidyl-tyrosine Dephosphorylation
Intracellular Signal Transduction
Negative Regulation Of Insulin Receptor Signaling Pathway
Multicellular Organismal Homeostasis
Angiotensin Maturation
Proteolysis
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Negative Regulation Of Plasminogen Activation
Negative Regulation Of Protein Binding
Neutrophil Degranulation
COPII Vesicle Coating
Proteolysis Involved In Cellular Protein Catabolic Process
Regulation Of Neuron Death
Pathways
Metabolism of Angiotensinogen to Angiotensins
COPII-mediated vesicle transport
Lysosome Vesicle Biogenesis
Cargo concentration in the ER
Neutrophil degranulation
Drugs
Diseases
GWAS
Blood protein levels (
30072576
29875488
)
Hematocrit (
32888494
)
Inflammatory bowel disease (
23128233
)
Lymphocyte counts (
32888494
)
Mean platelet volume (
22139419
24026423
32888494
27863252
)
Monocyte count (
32888494
)
Platelet count (
32888494
)
Platelet distribution width (
32888494
27863252
)
Interacting Genes
150 interacting genes:
ADCK5
AMMECR1
AP1S2
AQP1
ARID5A
ASB3
AXL
BAHD1
BLZF1
BRCA1
C11orf87
C1orf94
CATSPER1
CCDC33
CNNM3
COX6B2
CPSF7
CRX
CSNK1E
CTSZ
DCAF11
DCAF8
DDIT4L
DLC1
DOK3
DZIP1
DZIP3
EGFR
ENKD1
EPB41L4A
EPDR1
EPS8L2
ERBB2
ERBB3
ERBB4
FABP7
FAM114A1
FAM228A
FASLG
FGF21
FGFR1
FOXO1
GATA1
GBA3
GFI1B
HOXA1
HOXB9
HOXC8
HUWE1
ID2
IHO1
INO80B
ITGB3
ITGB5
ITGB7
KCTD9
KIF1A
KIT
KPRP
KRT76
KRTAP1-3
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP11-1
KRTAP12-2
KRTAP12-3
KRTAP13-1
KRTAP13-2
KRTAP23-1
KRTAP3-1
KRTAP4-4
KRTAP6-3
LASP1
LPXN
LUZP4
MET
MGAT5B
MPEG1
MT2A
MTDH
MYBPHL
MYH7B
MYPOP
NBPF19
NMU
NOTCH2NLA
NT5C
NUBP2
OBSL1
OTX1
PATZ1
PER1
PHF1
PIN1
PKP1
PLB1
PLK3
PLSCR3
POLR1H
POLR3F
PRR22
RAMAC
RBAK
RBPMS
REEP6
REL
RFT1
RNF6
SDCCAG8
SERTAD2
SH2B3
SHFL
SOCS7
SORBS3
SPATA12
SPRY2
SPRY4
SUSD2
SUV39H1
TBC1D16
TCP10L
TEKT3
TEKT5
TENT5A
TENT5B
TFAP2D
TLE5
TM4SF19
TRIM8
TSC1
TWSG1
USP54
WAC
WDFY3
ZCCHC14
ZIM2
ZNF134
ZNF205
ZNF250
ZNF417
ZNF497
ZNF575
ZNF586
ZNF587
ZNF648
ZNF655
ZNF688
ZNF837
21 interacting genes:
BACH2
BANP
CYSRT1
FHL5
HSF2BP
KRT35
KRT40
KRTAP1-1
KRTAP10-1
KRTAP10-10
KRTAP2-3
KRTAP2-4
KRTAP3-3
KRTAP5-9
KRTAP6-3
MID2
MTUS2
NBPF19
NOTCH2NLA
PLSCR1
TNS2
Entrez ID
23371
1522
HPRD ID
16256
04410
Ensembl ID
ENSG00000111077
ENSG00000101160
Uniprot IDs
A0A024RB48
Q63HR2
Q9UBR2
PDB IDs
2DKQ
2KNO
2L6K
2LOZ
3HQC
1DEU
1EF7
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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